Abstract
Peritoneal cancer and its complications remain among the greatest challenges in oncology. The underlying neoplasia and its typical complications are major determinants of prognosis; complications can occur at various time points in the course of the disease. Clinical symptoms can be divided into two main subgroups: (1) mechanical disorders of the digestive tract, mechanical ileus/subileus, constipation, paradoxical diarrhea, pain, and compression of intra-abdominal organs (e.g., renal congestion), and (2) disorders of the autonomic nervous system of the abdomen, neuropathic pain, difficulties emptying bowels, feeling of fullness, and paralytic ileus/subileus.
Treatment of advanced disease mostly includes systemic chemotherapy. Typical related complications and side effects are nausea/vomiting, diarrhea, constipation, infections, and the fatigue syndrome. Multidisciplinary approaches including a palliative care assessment are necessary for an optimal care of peritoneal cancer patients.
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Sinn, M. (2021). Complications in the Palliative Chemotherapy of Peritoneal Cancer. In: Rau, B., Königsrainer, A., Mohamed, F., Sugarbaker, P.H. (eds) Peritoneal Tumors and Metastases. Springer, Cham. https://doi.org/10.1007/978-3-030-62640-2_28
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