Skip to main content
Log in

Improved reproducibility of citric acid production in Aspergillus niger

  • Published:
Biotechnology Letters Aims and scope Submit manuscript

Summary

We report the derivation of Aspergillus niger strains having a lower standard deviation in citric acid production by the use of 60Co gamma radiation and by the parasexual cycle. On the basis of the results obtained by isolating diploids and segregants, diploidization seems to be sufficient for reducing variability. The implications of these results in terms of improvement of industrial strains are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Ball C. and Azevedo J.L. (1976) In: MacDonald,K.D., Ed. Proceedings of the 2 nd International Symposium on the Genetics of Industrial Microorganisms, pp. 243–251, Academic Press, New York.

    Google Scholar 

  • Bonatelli Jr. R. (1978) Ciência e Cultura, Simpósio II, 123–127.

  • Bonatelli Jr. R. (1981) Ph.D. Thesis, University of São Paulo, Brasil.

    Google Scholar 

  • Bonatelli Jr. R., Azevedo J.L. and Valent G.U. (1982) Braz. J. Genet.5, 483–492.

    Google Scholar 

  • Chang L.T. and Terry C.A. (1973) Appl. Microbiol.25,890–895.

    Google Scholar 

  • Doelger W.P. and Prescott S.C. (1934) Ind.Eng.Chem.26,1142–1149.

    Google Scholar 

  • Foster J.W. and Davis H. (1949) Bulletim of the Torrey Botanical Club76, 174–176.

    Google Scholar 

  • Gardner J.F. James L.V. and Rubbo S.D. (1956) J.Gen.Microbiol.14, 228–237.

    Google Scholar 

  • Lockwood L.B. (1975) In: Smith J.E. and Berry D.R.Eds. The Filamentous Fungi, vol I, pp. 140–157, Edward Arnold Ltd., London.

    Google Scholar 

  • MacDonald K.D. (1968) Nature218, 371–372.

    Google Scholar 

  • Marier J.R. and Boulet M. (1958) J. Dairy Sci.41, 1683–1692.

    Google Scholar 

  • Perlman D. and Sih C.J. (1960) Prog.Ind.Microbiol.2,168–194.

    Google Scholar 

  • Pontecorvo G. Roper J.A. Hemmons L.M. MacDonald K.D. and Bufton A.W.J. (1953) Adv. Genet.5, 141–238.

    Google Scholar 

  • Roper J.A. (1952) Experientia (Basel) 8, 14–15.

    Google Scholar 

  • Silva J.C. and Azevedo J.L. (1978) Braz. J. Genet.1, 41–49.

    Google Scholar 

  • Tavares F.C.A. and Azevedo J.L. (1974) In: 2 nd International Symposium on Genetics of Industrial Microorganisms 2, 86 (Abstract).

    Google Scholar 

  • Trumpy B.H. and Millis N.F. (1963) J.Gen.Microbiol.30,381–393.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bonatelli, R., De Azevedo, J.L. Improved reproducibility of citric acid production in Aspergillus niger . Biotechnol Lett 4, 761–766 (1982). https://doi.org/10.1007/BF00134674

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00134674

Keywords

Navigation