Abstract
Beat-to-beat measurements with 30 micro-seconds accuracy were carried out in order to determine the chronotropic effects on the heart ofDaphnia magna induced by adrenoceptor agonists and antagonists dissolved in water. Agonists and antagonists were either ineffective or lowered the heart frequency (P < 0.05). In addition, the negative chronotropic effect of the agonist epinephrine could not be blocked by the antagonist propranolol. It may, therefore, well be that the drug actions were not mediated through adrenoceptors.
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Postmes, T.J., Prick, R. & Brorens, I. The deceleration of the heart frequency in the waterfleaDaphnia magna by adrenoceptor agonists and antagonists. Hydrobiologia 171, 141–148 (1989). https://doi.org/10.1007/BF00008174
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DOI: https://doi.org/10.1007/BF00008174