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Abstract

Successful retracement in the laboratory under terrestrial conditions of synthesis of the first cell from progenitor thermal protein has been recorded (Fox et al., 1995; Enger and Ross, 1997). This retracement has benefited from recognition of some reversibility in molecular evolution (Atkinson and Fox, 1951; Fox et al., 1995a; Fox et al., 1995b). A number of other new advances were also required. Sequence analysis of amino acid residues was a method needed early (Fox, 1945). (While the 1945 prospectus preceded analysis of insulin and other related developments by other workers), the evolutionary applications led to recognition of self-sequencing of amino acids into polymers when heated, self-assembly of the resultant thermal proteins to first living cells (Fox, 1971; Fox et al., 1995; Enger and Ross, 1997) and a number of other advances.

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References

  • Atkinson, D.E. and Fox S.W. (1951). Synthesis of aromatic amino acids by mutant strains of Lactobacillusarabinosus. Arch. Biochem. Biophys 31, 212–223.

    Article  PubMed  CAS  Google Scholar 

  • Behe, M.J. (1996). Darwin’s Black Box, Simon and Schuster.

    Google Scholar 

  • Chela-Hores, J. and Raulin, F. (eds.) (1996). Chemical Evolution: Physics of the Origin and Evolution of Life. Kluwer Academic Publishers, Dordrecht.

    Google Scholar 

  • Crick, F. (1994). Interview with Jane Clark. J. Consciousness Studies 1, 15.

    Google Scholar 

  • De Duve, C. (1995). Vital Dust/Life as a Cosmic Imperative. Basic Books, New York, p. 93.

    Google Scholar 

  • Enger, E.D. and Ross, F.E. (1997). Concepts in Biology, Eighth Edition. Wm. C. Brown Publishers, Dubuque, IA, p. 362.

    Google Scholar 

  • Ferris, J. (1993). Catalysis and prebiotic RNA synthesis. Origins of Life/Evolution of Biosphere 23, 307–315.

    Article  CAS  Google Scholar 

  • Fox, S. W. (1945). Terminal amino acids in peptides and proteins. Advances Protein Chem., 2 pp. 155–177.

    Article  CAS  Google Scholar 

  • Fox, S.W. (1966). Experiments with a precellular model, in Conference on Theoretical Biology, NASA, De novo Cell Synthesis, G. J. Jacobs (ed). Kluwer Academic Publishers, p. 1–6.

    Google Scholar 

  • Fox, S.W. (Dec. 6, 1971). Chemical origins of cells-2. Chem. Eng. News 49, 46–53.

    Article  CAS  Google Scholar 

  • Fox, S.W. (1985). Protobiological Selforganization, in Structure and motion: Membranes, Nucleic Acids, and Proteins, E. Clementi, C. Corongiu, M.H. Sarma, and R.H. Sarma (eds). Adenine Press, Guilderland, N.Y., pp. 101–114.

    Google Scholar 

  • Fox, S.W. (1995). To cellular life and neurocellular assemblies, in Evolution, Biochemistry, and Related Areas of Phvsicochemical Biology, B. Poglazov et al (eds). Bach Institute of Biochemistry and ANKO, Moscow, pp. 161–175.

    Google Scholar 

  • Fox, S.W., Bahn P.R. et al. (1995). Experimental retracement of the origins of a protocell; it was also a protoneuron. in Chemical Evolution: Structure and Model of the First Cell, C. Ponnamperuma and J. Chela-Flores (eds). Kluwer Academic Publishers, Dordrecht, pp. 17–36.

    Chapter  Google Scholar 

  • Fox, S.W., Bahn P.R., Pappeiis A., and Yu, Bi. (1996). Experimental retracementof terrestrial origin of an excitable cell, in Chemical Evolution: Physics of the Origin and Evolution of Life. J. Chela-Flores and F. Raulin (eds). Kluwer Academic Publishers, Dordrecht, pp. 21–32.

    Chapter  Google Scholar 

  • Fox, S.W. and Dose, K. (1972) Molecular Evolution and the Origin of Life. W.H. Freeman and Co., San Francisco.

    Google Scholar 

  • Fox, S. W. and Middlebrook, M. (1954) Anhydrocopolymerization of amino acids under the influence of hypothetically primitive terrestrial conditions. Federation Proc. 13, 703.

    Google Scholar 

  • Heinz, B., Ried, W., and Dose, K. (1980). Thermal production of pteridines and flavins from amino acid mixtures. Angew. Chem. 91, 510–511.

    Article  Google Scholar 

  • Ishima, Y., Przybylski, A.T., and Fox, S.W. (1981). Electrical membrane phenomena in spherules from proteinoid and lecithin. BioSystems 13, 243–251.

    Article  PubMed  CAS  Google Scholar 

  • Jukes, T.H. (1997). Oparin and Lysenko. J. Mol. Evol. 45, 339–346.

    Article  PubMed  Google Scholar 

  • Lee, D.H., Granja, J.R., Martinez, J.A., Severin, K., and Ghadri, R. (1996). A self-replicating peptide. Nature 382 525–528.

    Article  PubMed  CAS  Google Scholar 

  • Nakashima, T. and Fox, S.W. (1980). Synthesis of peptides from amino acids and ATP with lysine-rich proteinoid. J. Mol. Evol. 15, 161–168.

    Article  PubMed  Google Scholar 

  • Nakashima, T. and Fox, S.W. (1981). Formation of peptides from amino acids by single or multiple additions of ATP to suspensions of nueleoproteinoid microparticles. BioSystems 14, 151–161.

    Article  PubMed  CAS  Google Scholar 

  • Negron-Mendoza, A. (1995). Alfonso L. Herrera, a Mexican pioneer in the studies of the origin of life. In Chemical Evolution; Structure and Model of the First Cell. C. Ponnamperuma and J. Chela-Flores (eds.) Kluwer Academic Publishers, pp. 11–13.

    Google Scholar 

  • Oro, J. (1996). Cosmic evolution, life and man. In Chemical Evolution: Physics of the Origin and Evolution of Life. J. Chela-Flores and F. Raulin (eds.) Kluwer Academic Publishers, pp. 3–19, especially pp. 6–11.

    Google Scholar 

  • Urey, H. C. (1952) The Planets, Yale University Press, p. 150 World Wide Web Address-(http://entropy.me.usouthal.edu/harbinger/articles/rel_sci/fox.html)

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Fox, S.W., Pappelis, A., Grubbs, R. (1998). The Origin of Mind and Life. In: Chela-Flores, J., Raulin, F. (eds) Exobiology: Matter, Energy, and Information in the Origin and Evolution of Life in the Universe. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5056-9_8

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  • DOI: https://doi.org/10.1007/978-94-011-5056-9_8

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