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Intermediate Filament Expression in Mouse Embryonic Stem Cells and Early Embryos

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Perspectives of Stem Cells

Abstract

In this work we discuss the expression of intermediate filament protein and synthesis in mouse oocytes and preimplantation murine embryos. Also we touch to epithelial differentiation and intermediate-sized filaments in early postimplantation embryos. After we analyse the intermediate filaments expression in primary mesenchymal cells in mouse embryo, we look to the expression of nestin and synemin during early embryogenesis and differentiation. Finally, we point out some questions to glial tumors and cytoskeletal markers of cells potentially pluripotent present in these tumors, as nestin and synemin proteins.

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Abbreviations

ES cells:

embryonic stem cells

EB:

embryonic bodies

GFAP:

glial fibrillary acidic protein

ICM:

inner cell mass

IF:

intermediate filament

KO:

knock-out

NF:

neurofilament

PE:

parietal endoderm

PNS:

peripheral nervous system

VE:

visceral endoderm

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Authors and Affiliations

  1. UPMC Univ Paris 6, UMR 7079, Paris, France

    Zhigang Xue, Araksya Izmiryan, Denise Paulin & Zhenlin Li

  2. Instituto de Ciências Biomédicas-Universidade Federal de Rio de Janeiro, Rio de Janeiro, Brazil

    Vivaldo Moura-Neto & Sheila Cristina de Souza Martins

  3. Laboratoire de Biologie du Développement, Paris, France

    Jean Christophe Larcher

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  1. Zhigang Xue
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  2. Vivaldo Moura-Neto
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Correspondence to Vivaldo Moura-Neto .

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  1. Inst. Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, São Paulo, 05508-900, Brazil

    Henning Ulrich

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Xue, Z. et al. (2010). Intermediate Filament Expression in Mouse Embryonic Stem Cells and Early Embryos. In: Ulrich, H. (eds) Perspectives of Stem Cells. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3375-8_5

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