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Inflammation and Atherosclerosis

  • Book
  • © 2012

Overview

Editors:
  1. Georg Wick

    1. Medical University Innsbruck, Innsbruck, Austria

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  2. Cecilia Grundtman

    1. Laboratory of Autoimmunity, Division of Experimental Pathophysiology, Biocenter, Innsbruck Medical University, Innsbruck, Austria

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  • Written by experts in the field of atherosclerosis and inflammation

  • Comprehensive insight into the history, clinical manifestations, mechanisms and treatment of inflammatory atherosclerotic diseases

  • Introduces new concepts and technologies

  • Gives a comprehensive account of the concept that inflammatory processes play a crucial role in the development of atherosclerosis

  • Describes new vaccination strategies

  • Includes supplementary material: sn.pub/extras

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Table of contents (31 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. Historical Reflections on the Inflammatory Aspects of Atherosclerosis

    • F. Javier Nieto
    Pages 1-17

  3. Morphology of Atherosclerotic Lesions

    • Maya Simionescu, Anca V. Sima
    Pages 19-37

  4. Clinical Manifestations of Atherosclerosis

    • Roland Klingenberg, Matthias Hasun, Roberto Corti, Thomas F. Lüscher
    Pages 39-58

  5. Intra-Aortic Hematopoietic Cells

    • Françoise Dieterlen-Lièvre, Thierry Jaffredo
    Pages 59-75

  6. The Vascular-Associated Lymphoid Tissue (VALT)

    • Georg Wick, Robert öllinger, Giovanni Almanzar
    Pages 77-86

  7. Vascular Endothelial Cells as Immunological Targets in Atheroscleroisis

    • Birgit Fogal, Jordan S. Pober
    Pages 87-114

  8. The Role of Adhesion Molecules and Intimal Dendritic Cells in the Initiation of Atherosclerosis

    • Jenny Jongstra-Bilen, Myron I. Cybulsky
    Pages 115-131

  9. Animal Models of Atherosclerosis

    • Cecilia Grundtman
    Pages 133-169

  10. A Darwinian-Evolutionary Concept for Atherogenesis: The Role of Immunity to HSP60

    • Georg Wick, Nicole Buhr, Gustav Fraedrich, Cecilia Grundtman
    Pages 171-196

  11. Mediators of Vascular Inflammation

    • Hafid Ait-Oufella, Ziad Mallat, Alain Tedgui
    Pages 197-217

  12. Pentraxins and Atherosclerosis

    • Elisa Barbati, Barbara Bottazzi, Alberico L. Catapano, Cecilia Garlanda, Roberto Latini, Alberto Mantovani et al.
    Pages 219-237

  13. Interleukin-33 and Atherosclerosis

    • Foo Y. Liew, Ashley M. Miller
    Pages 239-248

  14. Proteomics of Atherosclerosis

    • Mélanie Abonnenc, Manuel Mayr
    Pages 249-266

  15. Adipokines, Inflammation, and Atherosclerosis

    • Thomas M. Stulnig, Maximilian Zeyda
    Pages 267-288

  16. Natural Antibodies and Atherosclerosis

    • Dimitrios Tsiantoulas, Christoph J. Binder
    Pages 289-304

  17. NK/NKT Cells and Atherosclerosis

    • Marco Cavallari, Thérèse J. Resink, Gennaro De Libero
    Pages 305-330

  18. Macrophages and Atherosclerosis

    • Andrew C. Newby
    Pages 331-352

  19. Host Pattern Recognition Receptors (Toll-Like Receptors, RIG-I-Like Receptors, NOD-Like Receptors) and Atherosclerosis

    • Marc Feldmann, Claudia Monaco
    Pages 353-383

  20. Humoral Antibodies

    • A. Graham Pockley
    Pages 385-396
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Keywords

About this book

It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.

Editors and Affiliations

  • Medical University Innsbruck, Innsbruck, Austria

    Georg Wick

  • Laboratory of Autoimmunity, Division of Experimental Pathophysiology, Biocenter, Innsbruck Medical University, Innsbruck, Austria

    Cecilia Grundtman

About the editors

Cecilia Grundtman, PhD. Studies in Biomolecular Chemistry at the Södertörn Högskola in Stockholm, Sweden, graduation in 2002. In 2008, PhD from the Karolinska Institute in Stockholm, Department of Medicine, Rheumatology Unit, on “Pathogenetic Mechanism in Idiopathic Inflammatory Myopathies”. Since 2008 Lab Chief at the Laboratory of Autoimmunity, Division of Experimental Pathophysiology and Immunology, Biocenter, Medical University Innsbruck (MUI), Austria. Specialization in the field of immunological tolerance and the development of novel vaccines against atherosclerosis.

 

 

Georg Wick, MD, Professor. Medical Studies and Doctorate at the University of Vienna, Austria. Postdoctoral studies at the Center of General and Experimental Pathology and at the Department of Virology in Vienna. Research fellow at the Center for Immunology, State University of New York, Buffalo, USA. From 1975 to 2007 Professor and Chairman, Division of Experimental Pathophysiology and Immunology, Biocenter, Medical University Innsbruck (MUI), Austria. Achievements and specialization: autoimmunity, the immunology of aging, connective tissue immunopathology. Additional appointments among others as Founding Director of the Institute for Biomedical Aging Research of the Austrian Academy of Sciences in Innsbruck (1991 to 2003). President of The Austrian Science Fund (FWF, 2003-2005). Currently Professor emeritus and Head of the Laboratory of Autoimmunity, Biocenter, MUI.

Bibliographic Information

  • Book Title: Inflammation and Atherosclerosis

  • Editors: Georg Wick, Cecilia Grundtman

  • DOI: https://doi.org/10.1007/978-3-7091-0338-8

  • Publisher: Springer Vienna

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag/Wien 2012

  • Hardcover ISBN: 978-3-7091-0337-1Published: 07 December 2011

  • Softcover ISBN: 978-3-7091-1677-7Published: 01 March 2014

  • eBook ISBN: 978-3-7091-0338-8Published: 03 December 2011

  • Edition Number: 1

  • Number of Pages: X, 634

  • Topics: Immunology, Human Physiology, Endocrinology, Vaccine

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