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Biologic Knee Arthroplasty for Cartilage Injury and Early Osteoarthritis

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Bio-orthopaedics

Abstract

Injury to knee articular cartilage is a prominent cause of functional limitation that affects both genders over a wide range of ages. Retaining the native knee joint is often a priority for younger individuals who wish to maintain their active lifestyle. Due to improvements in surgical techniques and technology, a greater number of treatment options are becoming increasingly available to treat extensive areas of cartilage injury, including cases of early degenerative change. Cartilage restoration procedures, when combined with bony realignment surgery as indicated, have provided successful clinical outcomes in knees affected by multiple compartment cartilage injury. The technique of biologic arthroplasty of the knee joint, using cell-based cartilage repair technology with concurrent bony realignment, has been demonstrated to provide successful clinical outcomes in a wide range of cartilage lesion types, including cases that would typically be considered early osteoarthritis.

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Author information

Authors and Affiliations

  1. New York Presbyterian Hospital/Queens, New York, NY, USA

    Graeme P. Whyte M.D., M.Sc., F.R.C.S.C.

  2. O.A.S.I. Bioresearch Foundation Gobbi NPO, Via Amadeo 24, 20133, Milan, Italy

    Graeme P. Whyte M.D., M.Sc., F.R.C.S.C. & Alberto Gobbi M.D.

Authors
  1. Graeme P. Whyte M.D., M.Sc., F.R.C.S.C.
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  2. Alberto Gobbi M.D.
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Corresponding author

Correspondence to Alberto Gobbi M.D. .

Editor information

Editors and Affiliations

  1. O.A.S.I. Bioresearch Foundation NPO, Milan, Italy

    Alberto Gobbi

  2. Clínica do Dragão, Espregueira-Mendes Sports Centre – FIFA Medical Centre of Excellence, Porto, Portugal

    João Espregueira-Mendes

  3. Musculoskeletal and Joint Research Foundation, San Diego, California, USA

    John G. Lane

  4. Department of Orthopedics, Acibadem University, Istanbul, Turkey

    Mustafa Karahan

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Whyte, G.P., Gobbi, A. (2017). Biologic Knee Arthroplasty for Cartilage Injury and Early Osteoarthritis. In: Gobbi, A., Espregueira-Mendes, J., Lane, J., Karahan, M. (eds) Bio-orthopaedics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54181-4_41

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  • DOI: https://doi.org/10.1007/978-3-662-54181-4_41

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-54180-7

  • Online ISBN: 978-3-662-54181-4

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