Abstract
Positron emission tomography (PET) now provides the opportunity for local studies of brain functions such as blood flow and oxygen and glucose, and aminoacid consumption. A reduction in mean value of one of these biochemical parameters is not always followed by the same decrease in the others, and these discrepancies are particularly interesting in diseased nervous tissue.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bustany P, Sargent T, Saudubray JM et al. (1981) Regional human brain uptake and protein incorporation of 11C-L-methionine studied in vivo with PET. J Cereb Blood Flow Metabol 1 [Supp11]: S 17-S 18
Comar D, Cartron JC, Mazière M et al. (1976) Labelling and metabolism of methionine–Methyl 11C. Eur J Nucl Med 1: 11–14
Frackowiak RSJ, Pozzilli C, Legg NJ et al. (1981) Regional cerebral oxygen supply and utilization in dementia. Brain 104: 753–778
Grubb RL, Raichle ME, Gado MH et al. (1977) Cerebral blood flow, oxygen utilization, and blood volume in dementia. Neurology 27: 905–910
Mazière B, Loc’h C, Ricordel Y et al. (1982) Regional cerebral blood pool measurements using 68Ga labeled proteins. WFNMB Meeting Abstracts, Paris, September 1982, Vol 1. Pergamon Press, pp 666–669
Wasterlain CG, Dwyer B (1982) Generalized neonatal seizures in primates: focal inhibition of protein synthesis in vulnerable regions. Neurology: A 169 (abstract)
Willmore LJ, Dunn AI, Rubin JJ (1981) Changes in (3H) lysine incorporation into protein in a seizure focus in rat isocortex. Brain Res Bull 6: 463–466
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Bustany, P. et al. (1983). Local Brain Protein Metabolism in Dementia and Schizophrenia: In Vivo Studies with 11C-L-Methionine and Positron Emission Tomography. In: Heiss, WD., Phelps, M.E. (eds) Positron Emission Tomography of the Brain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95428-3_25
Download citation
DOI: https://doi.org/10.1007/978-3-642-95428-3_25
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-12130-5
Online ISBN: 978-3-642-95428-3
eBook Packages: Springer Book Archive