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Clostridium botulinum C3 ADP-Ribosyltransferase

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ADP-Ribosylating Toxins

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 175))

Abstract

During the last few years various clostridial ADP-ribosylating exoenzymes have been described. These exoenzymes can be divided into two groups. One group is represented by clostridial cytotoxins which are characterized by their ability to ADP-ribosylate actin. Furthermore, all these toxins are binary in structure and consist of a binding component and an unlinked ADP-ribosyltransferase. Members of this family of clostridial ADP-ribosylating toxins are Clostridium botulinum C2 toxin, Clostridium perfringens toxin, and Clostridium spiroforme toxin. These toxins are described in detail by Aktories et al., in this volume. The other group of clostridial ADP-ribosylating exoenzymes is represented by C. botulinum ADP-ribosyltransferase C3 and by the novel ADP-ribosylating Clostridium limosum exoenzyme.

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Authors and Affiliations

  1. Institut für Pharmakologie und Toxikologie, Universität des Saarlandes, 6650, Homburg, Germany

    K. Aktories, C. Mohr & G. Koch

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  1. K. Aktories
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  2. C. Mohr
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  3. G. Koch
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  1. Institut für Pharmakologie und Toxikologie, Universität des Saarlands, 6650, Homburg/saar, Germany

    Klaus Aktories

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Aktories, K., Mohr, C., Koch, G. (1992). Clostridium botulinum C3 ADP-Ribosyltransferase. In: Aktories, K. (eds) ADP-Ribosylating Toxins. Current Topics in Microbiology and Immunology, vol 175. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76966-5_6

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  • DOI: https://doi.org/10.1007/978-3-642-76966-5_6

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