Abstract
The detailed analysis of physiology and pathophysiology in man is a difficult and frequently impossible task. In many instances, volunteers will not serve as experimental subjects; multiple variables cannot be simultaneously explored; and placebo-controlled trials are confounded by intervening social dynamics. Animals, used instead as surrogates for man, then only provide approximate models of uncertain relevance. For most diseases affecting man, even animal models are unavailable, precisely because these diseases affect only man.
HK and RN are from SyStemix, Inc. ML is from the Cancer Biology Research Laboratory and ILW from the Laboratory of Experimental Oncology
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© 1989 Springer-Verlag Berlin · Heidelberg
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McCune, J.M., Kaneshima, H., Lieberman, M., Weissman, I.L., Namikawa, R. (1989). The Scid-hu Mouse: Current Status and Potential Applications. In: Bosma, M.J., Phillips, R.A., Schuler, W. (eds) The Scid Mouse. Current Topics in Microbiology and Immunology, vol 152. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74974-2_22
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DOI: https://doi.org/10.1007/978-3-642-74974-2_22
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