Skip to main content
SpringerLink
Log in

Structure and Biosynthesis of the Capsular Antigens of Escherichia coli

  • Conference paper
Bacterial Capsules

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 150))

Abstract

A characteristic feature of gram-negative bacteria, to which Escherichia coli belong, is the presence of an outer membrane on the external side of the murein sacculus. This layer consists of proteins, lipoproteins, phospholipids, and lipopolysaccharides (LPSs). LPSs of smooth wild-type bacteria, consisting of lipid A, core, and O-specific polysaccharide, are O antigens and those of rough mutants consisting only of lipid A and core are R antigens (Jannand Westphal1975; Jannand Jann1984).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abe C, Schmitz S, Jann B, Jann K (1988) Monoclonal antibodies against O and K antigens of uro-pathogenic E. coli 04:K12:H- as opsonins. FEMS Microbiol Lett 51: 153–158

    CAS  Google Scholar 

  • Ahrens R, Brade H, Jann B, Jann K (1988) Structure of the K74 antigen from Escherichia coli 044: K74:H18, capsular polysaccharide containing furanosidic ßKDO residues. Carbohydr Res 179: 223–231

    Article  PubMed  CAS  Google Scholar 

  • Altman E, Dutton GGS (1985) Chemical and structural analysis of the capsular polysaccharide from Escherichia coli 09: K28(A) : H- (K28 antigen). Carbohydr Res 138: 293–303

    Article  PubMed  CAS  Google Scholar 

  • Anderson AN, Parolis H (1988) Structural investigations of E. coli K55 capsular polysaccharide using bacteriophage degradation (Abstr) 14th Carbohydrate Symposium, Stockholm, August 1988

    Google Scholar 

  • Anderson AN, Parolis H, Parolis LAS (1987) Structural investigation of the capsular polysaccharide from Escherichia coli O9: K37 (A84 a). Carbohydr Res 163: 81–90

    Article  PubMed  CAS  Google Scholar 

  • Bax A, Summers MF, Egan W, Guirgis N, Schneerson R, Robbins JB, Ørskov F, et al. (1988) Structural studies of the Escherichia coli K93 and K53 capsular polysaccharides. Carbohydr Res 173: 53–64

    Article  PubMed  CAS  Google Scholar 

  • Bayer ME, Thurow H (1977) Polysaccharide capsule of Escherichia coli : microscope study of its size, structure, and sites of synthesis. J Bacteriol 130: 911–936

    PubMed  CAS  Google Scholar 

  • Bayer ME, Carlemalm E, Kellenberger E (1985) Capsule of Escherichia coli K29: ultrastructural preservation and immunoelectron microscopy. J Bacteriol 162: 985–991

    PubMed  CAS  Google Scholar 

  • Bhattacharjee AK, Jennings HJ, Kenny CP (1978) Structural elucidation of the 3-deoxy-D-manno- octulosonic acid containing meningococcal 29-e capsular polysaccharide antigen using carbon-13 nuclear magnetic resonance. Biochemistry 17: 645–651

    Article  PubMed  CAS  Google Scholar 

  • Björndal H, Lindberg B, Lönngren I, Nilsson K, Nimmich W (1972) Structural studies on the Klebsiella O group 4 lipopolysaccharide. Acta Chem Scand 26: 1269–1271

    Article  PubMed  Google Scholar 

  • Boulnois GJ, Roberts IS, Hodge R, Hardy KR, Jann KB, Timmis KN (1987) Analysis of the Kl capsule biosynthesis genes of Escherichia coli : definition of three functional regions for capsule production. Mol Gen Genet 208: 242–246

    Article  PubMed  CAS  Google Scholar 

  • Branefors-Helander P, Kenne L, Lindberg B, Peterson K, Unger P (1981) Structural studies of two capsular polysaccharides elaborated by different strains of Haemophilus influenzae type e. Carbohydr Res 88:77–84

    Article  PubMed  CAS  Google Scholar 

  • Chakraborty AK, Friebolin H, Stirm S (1980) Primary structure of the Escherichia coli serotype K30 capsular polysaccharide. J Bacteriol 141: 971–972

    PubMed  CAS  Google Scholar 

  • Choy YM, Fehmel F, Frank N, Stirm S (1975) Escherichia coli capsule bacteriophages. VI. Primary structure of the bacteriophage 29 receptor, the E. coli serotype 29 capsular polysaccharide. J Virol 16: 581–590

    PubMed  CAS  Google Scholar 

  • Curvall M, Lindberg B, Löngren J, Nimmich W (1973) Structural studies on the Klebsiella O group 3 lipopolysaccharides. Acta Chem Scand 27: 2645–2649

    Article  PubMed  CAS  Google Scholar 

  • Dengler T, Jann B, Jann K (1985) Structure of the K95 antigen from Escherichia coli O75:K95:H5, a capsular polysaccharide containing furanosidic KDO-residues. Carbohydr Res 142: 269–276

    Article  PubMed  CAS  Google Scholar 

  • Dengler T, Jann B, Jann K (1986) Structure of the serine-containing capsular polysaccharide K40 antigen from Escherichia coli O8: K40:H9. Carbohydr Res 150: 233–240

    Article  PubMed  CAS  Google Scholar 

  • Dengler T, Himmelspach K, Jann B, Jann K (1988) Structure of the capsular K3 antigen of Escherichia coli O4: K3 : H44, a polysaccharide containing a 4-deoxy-2-hexulosonie acid. Carbohydr Res 178: 191–201

    Article  PubMed  CAS  Google Scholar 

  • Dutton GGS, Kuma-Mintah A (1987) Structure of Escherichia coli capsular antigen K34. Carbohydr Res 169: 213–220

    Article  PubMed  CAS  Google Scholar 

  • Dutton GGS, Parolis H, Parolis LAS (1987) The structure of the neuraminic acid containing capsular polysaccharide of E. coli serotype K9. Carbohydr Res 170: 193–206

    Article  PubMed  CAS  Google Scholar 

  • Dutton GGS, Kuma-Mintah A, Ng S (1988) Structural studies on the capsular polysaccharide of E. coli serotype K31 (Abstr) 14th International Carbohydrate Symposium, Stockholm, August 1988

    Google Scholar 

  • Echarti CE, Hirschei B, Boulnois GJ, Varley JM, Waldvogel F, Timmis KN (1983) Cloning and analysis of the K1 capsule biosynthesis genes of Escherichia coli : lack of homology with Neisseria meningitidis group B DNA sequences. Infect Immun 41: 54–60

    PubMed  CAS  Google Scholar 

  • Edelman GM (1985) Cell adhesion and molecular processes of morphogenesis. Annu Rev Biochem 54: 135–169

    Article  PubMed  CAS  Google Scholar 

  • Finke A, Roberts I, Pazzani C, Boulnois G, Jann K (1989) Activity of CMP-KDO synthetase in Escherichia coli expressing the capsular K5 polysaccharide — implication for biosynthesis of the K5 polysaccharide. J Bacteriol 171: 374–379

    Google Scholar 

  • Finne J (1982) Occurrence of unique polysialosyl carbohydrate units in glycoproteins of developing brain. J Biol Chem 257: 11966–11970

    PubMed  CAS  Google Scholar 

  • Glode MP, Robbins JB, Lin TY, Gotschlich EC, Ørskov I, Ørskov F (1977) Cross antigenicity and immunogenicity between capsular polysaccharides of group C Neisseria meningitidis and of Escherichia coli K92. J Infect Dis 135: 94–102

    Article  PubMed  CAS  Google Scholar 

  • Gotschlich EC, Fraser BA, Nishimura O, Robbins JB, Liu T-Y (1981) Lipid on capsular polysaccharides of gram-negative bacteria. J Biol Chem 256: 8915–8921

    PubMed  CAS  Google Scholar 

  • Gupta DS, Jann B, Schmidt G, Golecki JR, Ørskov I, Ørskov F, Jann K (1982) Coliphage K5, specific for E. coli exhibiting the capsular K5 antigen. FEMS Microbiol Lett 14: 75–78

    Article  Google Scholar 

  • Heidelberger M, Nimmich W (1976) Immunochemical relationships between bacteria belonging to two separate families: Pneumococci and Klebsiella. Immunochemistry 13: 67–80

    Article  PubMed  CAS  Google Scholar 

  • Hoffman S, Sorkin BC, White PC, Brackenbury R, Mailhammer R, Rutishauser U, Cunningham BA, Edelman GM (1982) Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes. J Biol Chem 257: 7720–7729

    PubMed  CAS  Google Scholar 

  • Hofmann P, Jann B, Jann K (1985 a) Structure of the amino acid-containing capsular polysaccharide (K54 antigen) from Escherichia coli O6:K54:H10. Carbohydr Res 139: 261–271

    PubMed  CAS  Google Scholar 

  • Hofmann P, Jann B, Jann K (1985 b) Structure of the fructose-containing K52 capsular polysaccharide of uropathogenic Escherichia coli O4:K52:H-. Eur J Biochem 147: 601–609

    Article  PubMed  CAS  Google Scholar 

  • Hungerer D, Jann K, Jann B, Ørskov F, Ørskov I (1967) Immunochemistry of K antigens of Escherichia coli. 4. The K antigen of E. coli O9:K30:H12. Eur J Biochem 2: 115–126

    Article  PubMed  CAS  Google Scholar 

  • Jann B, Jann K, Schmidt G, Ørskov F, Ørskov I (1971) Comparative immunochemical studies of the surface antigens of Escherichia coli strains O8:K87(B>):H19 and (O32):K87(B>):H45. Eur J Biochem 23: 515–522

    Article  PubMed  CAS  Google Scholar 

  • Jann B, Hofmann P, Jann K (1983) Structure of the 3-deoxy-D-manno-octulosonic acid-(KDO)-containing capsular polysaccharide (K14 antigen) from Escherichia coli O6:K14:H31. Carbohydr Res 120: 131–141

    Article  PubMed  CAS  Google Scholar 

  • Jann B, Dengler T, Jann K (1985) The capsular (K51) antigen of Escherichia coli O1 :K51 :H-, an O-acetylated poly-N-acetylglucosamine phosphate. FEMS Microbiol Lett 29: 257–261

    CAS  Google Scholar 

  • Jann B, Ahrens R, Dengler T, Jann K (1988) Structure of the capsular polysaccharide (K19 antigen) from uropathogenic Escherichia coli O25:K19:H12. Carbohydr Res 177: 273–277

    Article  PubMed  CAS  Google Scholar 

  • Jann K, Jann B (1984) Structure and biosynthesis of O-antigens. In: Rietschel ET (ed) Chemistry of endotoxin. Elsevier, Amsterdam, pp 138–186 (Handbook of endotoxin, vol 1)

    Google Scholar 

  • Jann K, Jann B (1987) Polysaccharide antigens of Escherichia coli. Rev Infect Dis [Suppl [5] 9:517–526

    Article  Google Scholar 

  • Jann K, Schmidt MA (1980) Comparative chemical analysis of two variants of the Escherichia coli K2 antigens. FEMS Microbiol Lett 7: 79–81

    Article  CAS  Google Scholar 

  • Jann K, Westphal O (1975) Microbial polysaccharides. In : Sela M (ed) The antigens, vol 3. Academic, New York, pp 1–123

    Google Scholar 

  • Jann K, Jann B, Ørskov F, Ørskov I, Westphal O (1965) Immunchemische Untersuchungen an K Antigenen von Escherichia coli. II. Das K Antigen von E. coli O8:K42(A):H-. Biochem Z 342: 1–22

    PubMed  CAS  Google Scholar 

  • Jann K, Jann B, Schneider KF, Ørskov F, Ørskov I (1968) Immunochemistry of K antigen of Escherichia coli. 5. The K antigen of E. coli O8 : K27(A): H-. Eur J Biochem 5: 456–465

    Article  PubMed  CAS  Google Scholar 

  • Jann K, Jann B, Schmidt MA, Vann WF (1980) Structure of the Escherichia coli K2 capsular antigen, a teichoic acid like polymer. J Bacteriol 143: 1108–1115

    PubMed  CAS  Google Scholar 

  • Jansson PE, Lönngren J, Widmalm G, Leontein K, Slettengren K, Svenson SB, Wrangsell G, et al. (1985) Structural studies of the O-antigen polysaccharides of Klebsiella 05 and Escherichia coli 08. Carbohydr Res 145: 59–66

    Article  PubMed  CAS  Google Scholar 

  • Jennings HJ, Rosell KG, Johnson KG (1982) Structure of the 3-deoxy-D-manno-octulosonic acid containing polysaccharide (K6 antigen) from Escherichia coli LP 1092. Carbohydr Res 105: 45–56

    Article  PubMed  CAS  Google Scholar 

  • Kasper DL, Winkelhage JL, Zollinger WD, Brandt BL, Artenstein MS (1973) Immunochemical similarity between polysaccharide antigens of Escherichia coli O7: K1(L):NM and group B Neisseria meningitidis. J Immunol 110: 262–268

    PubMed  CAS  Google Scholar 

  • Kauffmann F (1954) Enterobacteriaceae, 2nd edn. Munksgaard, Copenhagen

    Google Scholar 

  • Kauffmann F, Vahlne G (1945) Über die Bedeutung des serologischen Formenwechsels für die Bakteriophagenwirkung in der Coli-Gruppe. Acta Pathol Microbiol Scand 22: 119–137

    Article  PubMed  CAS  Google Scholar 

  • Kuhn HM, Meier-Dieter U, Mayer H (1988) ECA, the enterobacterial common antigen. FEMS Microbiol Rev 54: 195–222

    CAS  Google Scholar 

  • Larsen JC, Ørskov I, Ørskov F, Schmidt MA, Jann B, Jann K (1980) Crossed Immunoelectrophoresis and chemical structural analysis used for characterization of two varieties of Escherichia coli K2 polysaccharide antigen. Med Microbiol Immunol 168: 191–200

    Article  PubMed  CAS  Google Scholar 

  • Lenter H, Jann B, Jann K (1989) Structure of the K16 antigen from Escherichia coli O7:K16:H-, a KDO containing capsular polysaccharide. Carbohydr. Res. in press

    Google Scholar 

  • Lindahl U (1972) Enzymes involved m the formation of the carbohydrate structure of heparin. Methods Enzymol 28: 676–684

    Article  Google Scholar 

  • Mäkelä PH, Stocker BAD (1969) Genetics of polysaccharide biosynthesis. Annu Rev Genet 3: 291–322

    Article  Google Scholar 

  • Masson L, Holbein BE (1985) Role of lipid intermediate(s) in the synthesis of serogroup B Neisseria meningitidis capsular polysaccharide. J Bacteriol 161: 861–867

    PubMed  CAS  Google Scholar 

  • Mayer H (1969) D-Mannosaminuronsäure-Baustein des K7 Antigens von Escherichia coli. Eur J Biochem 8: 139–145

    Article  PubMed  CAS  Google Scholar 

  • McGuire EJ, Binkley SB (1964) The structure and chemistry of colominic acid. Biochemistry 3: 247–251

    Article  PubMed  CAS  Google Scholar 

  • Navia JL, Riesenfeld J, Vann WF, Lindahl U, Rodén L (1983) Assay of N-acetylheparosan deacetylase with a capsular polysaccharide from Escherichia coli K5 as substrate. Anal Biochem 135: 134–140

    Article  PubMed  CAS  Google Scholar 

  • Ørskov F, Ørskov I, Sutton A, Schneerson R, Lind W, Egan W, Hoff GE, Robbins JR (1979) Form variation in Escherichia coli Kl : determined by O-acetylation of the capsular polysaccharide. J Exp Med 149: 669–685

    Article  PubMed  Google Scholar 

  • Ørskov F, Sharma V, Ørskov I (1984) Influence of growth temperature on the development of Escherichia coli polysaccharide K antigens. J Gen Microbiol 130: 2681–2684

    PubMed  Google Scholar 

  • Ørskov I, Nyman K (1974) Genetic mapping of the antigenic determinants of two polysaccharide K antigens, K10 and K54, in Escherichia coli. J Bacteriol 120: 43–51

    PubMed  Google Scholar 

  • Ørskov I, Ørskov F, Jann B, Jann K (1977) Serology, chemistry and genetics of O and K antigens of Escherichia coli. Bacteriol Rev 41: 667–710

    PubMed  Google Scholar 

  • Paakkanen J, Gotschlich EC, Mäkelä PH (1979) Protein K: a new major outer membrane protein found in encapsulated Escherichia coli. J Bacteriol 139: 835–841

    PubMed  CAS  Google Scholar 

  • Parolis LAS, Parolis H (1988) Structural studies on the capsular antigen E. coli K8 (Abstr). 14th International Carbohydrate Symposium, Stockholm, August 1988

    Google Scholar 

  • Parolis LAS, Parolis H, Dutton GGS (1986) Structural studies of the O antigen polysaccharide of Escherichia coli O9 a. Carbohydr Res 155: 272–276

    Article  PubMed  CAS  Google Scholar 

  • Peters H, Jürs M, Jann B, Jann K, Timmis KN, Bitter-Suermann D (1985) Monoclonal antibodies to enterobacterial common antigen and to Escherichia coli lipopolysaccharide outer core: demonstration of an antigenic determinant shared by enterobacterial common antigen and E. coli K5 capsular polysaccharide. Infect Immun 50: 459–466

    PubMed  CAS  Google Scholar 

  • Prehm P, Jann B, Jann K (1976) The O9 antigen of Escherichia coli structure of the polysaccharide chain. Eur J Biochem 67: 53–56

    Article  PubMed  CAS  Google Scholar 

  • Reske K, Jann K (1972) The 08 antigen of Escherichia coli. Structure of the polysaccharide chain. Eur J Biochem 31: 320–328

    Article  PubMed  CAS  Google Scholar 

  • Robbins JB, Schneerson R, Liu T-Y, Schiffer MS, Schiffman G, Myerowitz RL, McCracken GH, et al. (1975) Cross-reacting bacterial antigens and immunity to disease caused by encapsulated bacteria. In: Neter E, Milgram F (eds) The immune system and infections 1 diseases. 4th Int Convoc Immunol, Buffalo NY. Karger, Basel, pp 218–241

    Google Scholar 

  • Roberts IS, Mountford R, High N, Bitter-Suermann D, Jann K, Timmis K, Boulnois G (1986) Molecular cloning and analysis of genes for production of K5, K7, K12 and K92 polysaccharides in Escherichia coli. J Bacteriol 168: 1228–1233

    PubMed  CAS  Google Scholar 

  • Roberts IS, Mountford R, Hodge R, Jann KB, Boulnois GJ (1988) Common organization of gene clusters for production of different capsular polysaccharides (K antigens) in Escherichia coli. J Bacteriol 170: 1305–1310

    PubMed  CAS  Google Scholar 

  • Roberts M, Roberts I, Korhonen TK, Jann K, Bitter-Suermann D, Boulnois GJ, Williams PH (1988) DNA probes for K-antigen (capsule) typing of Escherichia coli. J Clin Microbiol 26: 385–387

    PubMed  CAS  Google Scholar 

  • Rodriguez M-L, Jann B, Jann K (1988 a) Structure and serological characteristic of the capsular K4 antigen of Escherichia coli O5:K4:H4, a fructose containing polysaccharide with a chondroitin backbone. Eur J Biochem 177: 117–124

    Article  PubMed  CAS  Google Scholar 

  • Rodriguez M-L, Jann B, Jann K (1988 b) Comparative structural elucidation of the K18, K22 and K100 antigens of Escherichia coli as related ribosyl-ribitol phosphates. Carbohydr Res 173: 243–253

    Article  PubMed  CAS  Google Scholar 

  • Rodriguez M-L, Jann B, Jann K (1989) Structure and serological properties of the capsular Kl 1 antigen of Escherichia coli O13: K11 :H11, a fructose containing polysaccharide with a diglucosyl phosphate backbone. Carbohydr Res (in press)

    Google Scholar 

  • Rodriguez-Asparicio LB, Reglero A, Ortiz AI, Luengo JM (1988) A protein-sialyl polymer complex involved in colominic acid biosynthesis. Effect of tunicamycin. Biochem J 251: 589–596

    Google Scholar 

  • Schmidt G, Jann B, Jann K, Ørskov I, Ørskov F (1977) Genetic determinants of the synthesis of the polysaccharide capsular antigen K27(A) of Escherichia coli. J Gen Microbiol 100: 355–361

    PubMed  CAS  Google Scholar 

  • Schmidt MA, Jann K (1982) Phospholipid substitution of capsular (K) polysaccharide antigens from Escherichia coli causing extraintestinal infections. FEMS Microbiol Lett 14: 69–74

    Article  CAS  Google Scholar 

  • Schmidt MA, Jann K (1983) Structure of the 2-keto-3-deoxy-D-manno-octonic-acid-containing capsular polysaccharide (K12 antigen) of the urinary-tract-infective Escherichia coli O4:K12:H-. Eur J Biochem 131: 509–517

    Article  PubMed  CAS  Google Scholar 

  • Silver RP, Vann WF, Aaronson W (1984) Genetic and molecular analyses of Escherichia coli K1 antigen genes. J Bacteriol 157: 568–575

    PubMed  CAS  Google Scholar 

  • Silver RP, Aaronson W, Vann WF (1987) Translocation of capsular polysaccharides in pathogenic strains of Escherichia coli requires a 60 kilodalton periplasmic protein. J Bacteriol 169: 5489–5495

    PubMed  CAS  Google Scholar 

  • Tarcsay L, Jann B, Jann K (1971) Immunochemistry of the K antigens of Escherichia coli. The 87 antigen from E. coli O8: K87(B) :: H19. Eur J Biochem 23: 505–514

    Article  PubMed  CAS  Google Scholar 

  • Troy FA, McCloskey MA (1979) Role of a membranous sialtransferase complex in the synthesis of surface polymers containing polysialic acid in Escherichia coli. Temperature-induced alterations in the assembly process. J Biol Chem 254: 7377–7387

    PubMed  CAS  Google Scholar 

  • Troy FA, Frerman FE, Heath EC (1971) The biosynthesis of capsular polysaccharide in Aerobacter aerogenes. J Biol Chem 246: 118–133

    PubMed  CAS  Google Scholar 

  • Troy FA, Frerman FE, Heath EC (1972) Synthesis of capsular polysaccharides of bacteria. Methods Enzymol 28:602–624

    Article  Google Scholar 

  • Tsui F-P, Boykins RA, Egan W (1982) Structural and immunological studies of the Escherichia coli K7 (K56) capsular polysaccharide. Carbohydr Res 102: 263–271

    Article  PubMed  CAS  Google Scholar 

  • Unger FM (1981) The chemistry and biological significance of 3-deoxy-D-manno-2-octulosonic acid (KDO). Adv Carbohydr Chem 38:323–388

    Article  CAS  Google Scholar 

  • Vann WF, Jann K (1979) Structure and serological specificity of the K13 antigenic polysaccharide (K13 antigen) of urinary tract infective E. coli. Infect Immun 25: 85–92

    PubMed  CAS  Google Scholar 

  • Vann WF, Schmidt MA, Jann B, Jann K (1981) The structure of the capsular polysaccharide (K5 antigen) or urinary tract infective Escherichia coli O10:K5:H4. A polymer similar to desulfo heparin. Eur J Biochem 116: 359–364

    Article  PubMed  CAS  Google Scholar 

  • Vann WF, Soderstrom T, Egan W, Tsui F-P, Schneerson R, Ørskov I, Ørskov F (1983) Serological, chemical, and structural analyses of the Escherichia coli cross-reactive capsular polysaccharides K13, K20, and K23. Infect Immun 39: 623–629

    PubMed  CAS  Google Scholar 

  • Vasilieu UN, Zakharova IY (1976) The structure of the determinant group in O-specific polysaccharide of E. coli O20:K84:H34. Bioorg Chem 2: 199–206

    Google Scholar 

  • Whitfield C, Troy FA (1984) Biosynthesis and assembly of the polysialic acid capsule in Escherichia coli K 1. J Biol Chem 259: 12769–12775

    PubMed  CAS  Google Scholar 

  • Whitfield C, Adams DA, Troy FA (1984a) Biosynthesis and assembly of the polysialic acid capsule in Escherichia coli K1. Role of low-density vesicle fraction in activation of the endogenous synthesis of sialyl polymers. J Biol Chem 259: 12776–12780

    PubMed  CAS  Google Scholar 

  • Whitfield C, Vimr ER, Costerton W, Troy FA (1984b) Protein synthesis is required for in vivo activation of polysialic acid capsule synthesis in Escherichia coli K1. J Bacteriol 159: 321–328

    PubMed  CAS  Google Scholar 

  • Wicken AJ, Knox KW (1980) Bacterial cell surface amphiphiles. Biochem Biophys Acta 604: 1–26

    Article  PubMed  CAS  Google Scholar 

  • Zon G, Robbins JB (1983) 31P- and 13C-NMR-spectral and chemical characterization of the end-group and repeating-unit components of oligosaccharides derived by acid hydrolysis of Haemophilus influenzae type b capsular polysaccharide. Carbohydr Res 114: 103–121

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Max-Planck-Institut für Immunbiologie, Stübeweg 51, D-7800, Freiburg, Germany

    B. Jann & K. Jann

Authors
  1. B. Jann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. Jann
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Max-Planck-Institut für Immunbiologie, Stübeweg 51, 7800, Freiburg, Germany

    Klaus Jann  & Barbara Jann  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Jann, B., Jann, K. (1990). Structure and Biosynthesis of the Capsular Antigens of Escherichia coli . In: Jann, K., Jann, B. (eds) Bacterial Capsules. Current Topics in Microbiology and Immunology, vol 150. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74694-9_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-74694-9_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74696-3

  • Online ISBN: 978-3-642-74694-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation