Abstract
Regarding the marked asymmetric distribution of phospholipids in the erythrocyte membrane, which is characterized by the two choline containing phospholipids, sphingomyelin (SM) and phosphatidyl- choline (PC), being mainly located in the outer monolayer, whereas most of the phosphatidylethanolamine (PE) and all of the phosphatidylserine (PS) is found in the cytoplasmic leaflet (Zwaal, et.al. 1975, Op den Kamp, 1984), some important questions may be raised. These concern: (i) its constitution during biogenesis of the cell, (ii) its maintenance during the life span of the erythrocyte, and last but not least, (iii) its physiologic significance.
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van Deenen, L.L.M., Roelofsen, B., Op den Kamp, J.A.F. (1988). Transbilayer Organization and Mobility of Phospholipids in Normal and Pathologic Erythrocytes. In: Op den Kamp, J.A.F. (eds) Membrane Biogenesis. NATO ASI Series, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73184-6_2
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DOI: https://doi.org/10.1007/978-3-642-73184-6_2
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