Membrane Biogenesis

  • Jos A. F. Op den Kamp
Conference proceedings

Part of the NATO ASI Series book series (volume 16)

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Laurens L. M. van Deenen, Ben Roelofsen, Jos A. F. Op den Kamp
    Pages 15-28
  3. F. Tercé, M. Record, G. Ribbes, H. Chap, L. Douste-Blazy
    Pages 59-65
  4. Jos A. F. Op den Kamp, Andre Rawyler, Peter van der Schaft, Ben Roelofsen
    Pages 67-84
  5. J. A. Post, T. J. C. Ruigrok, J. M. J. Lamers, P. D. Verdouw, A. J. Verkleij
    Pages 103-118
  6. Howard Goldfine
    Pages 129-139
  7. Didier Sornette
    Pages 207-217
  8. Michael F. G. Schmidt, Marion Schmidt
    Pages 235-256
  9. B. de Kruijff, A. Rietveld, W. Jordi, T. A. Berkhout, R. A. Demel, H. Görrissen et al.
    Pages 257-269
  10. Wolfgang J. Schneider
    Pages 271-285

About these proceedings

Introduction

Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Keywords

Lipid Oligosaccharid bacteria biomembrane cell cell death endoplasmic reticulum escherichia coli glycoprotein membrane mutation protein proteins receptor regulation

Editors and affiliations

  • Jos A. F. Op den Kamp
    • 1
  1. 1.Laboratory of BiochemistryState University of UtrechtUtrechtThe Netherlands

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-73184-6
  • Copyright Information Springer-Verlag Berlin Heidelberg 1988
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-73186-0
  • Online ISBN 978-3-642-73184-6
  • About this book