Abstract
Morphinan alkaloids are an industrial commodity of plant origin. The market share of pharmaceuticals containing morphinans, predominantly codeine, is about 2.5% (Canada). The supply appears to be adequate, the price comparatively moderate. Restrictions, however, in the harvest and in the movement of raw and refined products due to socio-political implications has kindled interest in producing morphinan alkaloids by culturing poppy cells in vitro. The feasibility of developing such a process for industry would require fair accumulation of alkaloids in cells or their medium.
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Constabel, F. (1985). Morphinan Alkaloids from Plant Cell Cultures. In: Phillipson, J.D., Roberts, M.F., Zenk, M.H. (eds) The Chemistry and Biology of Isoquinoline Alkaloids. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70128-3_17
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DOI: https://doi.org/10.1007/978-3-642-70128-3_17
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