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The Myofibroblast in Neoplasia

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Tissue Repair and Fibrosis

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 93))

Abstract

Since its discovery in granulation tissue of healing wounds, now over a quarter of a century ago [22], the myofibroblast has been described in: (1) normal tissue; (2) diverse responses to injury and repair phenomena; (3) quasi-neoplastic proliferative conditions; (4) the stromal response to certain forms of neoplasia; and (5) benign and malignant neoplasms (for review [49]). In practical terms, the surgical pathologist is a daily witness to this panoply of myofibroblastic proliferation. An appropriate evaluation of the myofibroblast with regard to neoplasia is impossible without identifying briefly where these cells occur, and without defining this unique cell.

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Authors
  1. W. Schürch
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Editors and Affiliations

  1. GREF, Université Victor Segalen Bordeaux 2, 146, Rue Léo-Saignat, 33076, Bordeaux Cedex, France

    Alexis Desmoulière

  2. Départment de Nutrition, Université de Montréal, Pavillon Liliane-de-Stewart C. P. 6128, Succursale Centre-Ville, Montréal, Québec, H3C 3J7, Canada

    Beatriz Tuchweber

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© 1999 Springer-Verlag Berlin Heidelberg

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Schürch, W. (1999). The Myofibroblast in Neoplasia. In: Desmoulière, A., Tuchweber, B. (eds) Tissue Repair and Fibrosis. Current Topics in Pathology, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58456-5_14

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  • DOI: https://doi.org/10.1007/978-3-642-58456-5_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63603-5

  • Online ISBN: 978-3-642-58456-5

  • eBook Packages: Springer Book Archive

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