Abstract
The basic ideas of genetic load and the cost of natural selection are both from J. B. S. Haldane. In his early papers on natural selection (1924–1932), Haldane was concerned with both the dynamics and the statics of evolution. He emphasized that, although evolution depends on changes of gene frequency, nevertheless at any one time the population is in approximate equilibrium for most factors.
Paper number 1303 from the Laboratory of Genetics, University of Wisconsin. Some of the work reported here was supported by the National Institutes of Health (GM-15422).
This paper is dedicated to Professor Th. Dobzhansky for his seventieth birthday celebration and his long lasting leadership in experimental population genetics.
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Crow, J.F. (1970). Genetic Loads and the Cost of Natural Selection. In: Kojima, Ki. (eds) Mathematical Topics in Population Genetics. Biomathematics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46244-3_5
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