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Enzymatic Production of Xylitol: Current Status and Future Perspectives

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D-Xylitol

Abstract

Enzymatic production of bio-active compounds has several advantages over chemical synthesis. Enzymatic mediated reactions are generally considered safe, highly reproducible, economical and environmentally benign. Microbial mediated xylose fermentation for xylitol production is a conventional approach with several process complexities. Enzymatic conversion of xylose into xylitol offers a promising alternative towards the commercial production of xylitol on a large scale. This chapter will discuss enzymatic production (or in vitro) of xylitol with emphasis on enzymatic catalysis using coenzymes and their enzymatic regeneration methods. Furthermore, mechanisms of the enzymatic process, operational details, advantages and disadvantages in comparison with the traditional production methods of xylitol (chemical and microbial) have been discussed at length. Special emphasis is placed on the sustainable raw material alternatives for enzymatic production of xylitol using sugarcane bagasse as the main carbohydrate source.

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Acknowledgments

The authors gratefully acknowledge the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) (Grant n 2005/02840-0 and 2005/02866-9), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) for the financial support.

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Authors and Affiliations

  1. Campus Pato Branco, Coordenação de Química—COQUI, Universidade Tecnológica Federal do Paraná—UTFPR, Via do Conhecimento km 01, Fraron, Pato Branco, Paraná, 85503390, Brazil

    Ricardo de Freitas Branco

  2. Departamento de Biotecnologia-LOT, Estrada municipal do campinho s/n, Escola de Engenharia de Lorena-USP-EEL, Universidade de São Paulo, Lorena, São Paulo, 12602810, Brazil

    Anuj K. Chandel & Sílvio Silvério da Silva

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  1. Ricardo de Freitas Branco
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  2. Anuj K. Chandel
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  3. Sílvio Silvério da Silva
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Correspondence to Ricardo de Freitas Branco .

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Editors and Affiliations

  1. , Department of Biotechnology, University of São Paulo, Lorena-Estrada Municipal do Campinho, São Paulo, 12602810, Brazil

    Silvio Silvério da Silva

  2. , Department of Biotechnology, University of São Paulo, Lorena- Estrada Municipal do Campinho, São Paulo, 12602810, Brazil

    Anuj Kumar Chandel

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de Freitas Branco, R., Chandel, A.K., Silva, S.S.d. (2012). Enzymatic Production of Xylitol: Current Status and Future Perspectives. In: da Silva, S., Chandel, A. (eds) D-Xylitol. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31887-0_8

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