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Venous Physiology and Pathophysiology

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Current Management of Venous Diseases

Abstract

Veins are essentially tubes with valves that function as passive conduits for blood flow. Venous valve function ensures unidirectional flow, emptying of venous compartments, physiologic drainage, and flow of blood from the superficial to deep system. Normal valve closure also produces dynamic fracturing of the gravitational hydrostatic pressure and is essential for proper function of the peripheral muscle pumps. Chronic venous disease produces hemodynamic disturbances which result in the inability of valves, pumps, and conduits in the venous system to maintain a normal venous pressure and normal flow. These disturbances are primarily caused by venous reflux, obstruction, or a combination of both.

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  1. Department of Surgery, Division of Vascular Surgery, George Washington University Medical Faculty Associates, 1860 Town Center Drive, Suite 420, Reston, VA, 20190, USA

    James Laredo MD, PhD

  2. Department of Surgery, Division of Vascular Surgery, George Washington University Medical Center, 1860 Town Center Drive, Suite 420, Reston, VA, 20190, USA

    Byong Boong Lee MD, PhD

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  1. James Laredo MD, PhD
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  2. Byong Boong Lee MD, PhD
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Correspondence to James Laredo MD, PhD .

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  1. Section of Vascular Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA

    Cassius Iyad Ochoa Chaar

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Laredo, J., Lee, B.B. (2018). Venous Physiology and Pathophysiology. In: Chaar, C. (eds) Current Management of Venous Diseases . Springer, Cham. https://doi.org/10.1007/978-3-319-65226-9_2

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  • DOI: https://doi.org/10.1007/978-3-319-65226-9_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-65225-2

  • Online ISBN: 978-3-319-65226-9

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