Abstract
Bacteria regulate their own gene expression by producing, releasing and sensing chemical signals from the environment through a mechanism known as quorum sensing (QS). This bacterial cell-to-cell communication is responsible for controlling various biological traits in bacteria including the regulation of certain phenotypes and the expression of virulence factors that are responsible for pathogen–host association. Quorum quenching (QQ) or quorum sensing inhibitors (QSI) have been suggested as non-antibiotic therapeutic control to combat bacterial infections in aquaculture. Quorum quenchers are non-bacteriostatic organisms/molecules that can restrain the virulence of pathogens through interference with QS, enabling the host to use its own defence. Bacteria with quorum quenching capabilities are found in diverse environments and secretes secondary metabolites that interfere with the QS system which could render the bacterial infections in the host.
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Natrah, I., Muthukrishnan, S., Bossier, P. (2022). Quorum Quenching Bacteria as Probiotics. In: Austin, B., Sharifuzzaman, S. (eds) Probiotics in Aquaculture. Springer, Cham. https://doi.org/10.1007/978-3-030-98621-6_8
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