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Explaining Models by Propagating Shapley Values of Local Components

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Explainable AI in Healthcare and Medicine

Part of the book series: Studies in Computational Intelligence ((SCI,volume 914))

Abstract

In healthcare, making the best possible predictions with complex models (e.g., neural networks, ensembles/stacks of different models) can impact patient welfare. In order to make these complex models explainable, we present DeepSHAP for mixed model types, a framework for layer wise propagation of Shapley values that builds upon DeepLIFT (an existing approach for explaining neural networks). We show that in addition to being able to explain neural networks, this new framework naturally enables attributions for stacks of mixed models (e.g., neural network feature extractor into a tree model) as well as attributions of the loss. Finally, we theoretically justify a method for obtaining attributions with respect to a background distribution (under a Shapley value framework).

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References

  1. Goodman, B., Flaxman, S.: AI Magazine 38(3), 50 (2017)

    Article  Google Scholar 

  2. Holzinger, A., Biemann, C., Pattichis, C.S., Kell, D.B., arXiv preprint arXiv:1712.09923 (2017)

  3. Lundberg, S.M., Erion, G., Chen, H., DeGrave, A., Prutkin, J.M., Nair, B., Katz, R., Himmelfarb, J., Bansal, N., Lee, S.: CoRR abs/1905.04610http://arxiv.org/abs/1905.04610 (2018)

  4. Lundberg, S.M., Nair, B., Vavilala, M.S., Horibe, M., Eisses, M.J., Adams, T., Liston, D.E., Low, D.K.W., Newman, S.F., Kim, J., Lee, S.I.: bioRxiv. 10.1101/206540. https://www.biorxiv.org/content/early/2017/10/21/206540 (2017)

  5. Arcadu, F., Benmansour, F., Maunz, A., Willis, J., Haskova, Z., Prunotto, M.: NPJ Dig. Med. 2(1), 1 (2019)

    Article  Google Scholar 

  6. Lundberg, S.M., Lee, S.I.: Advances in Neural Information Processing Systems, pp. 4765–4774 (2017)

    Google Scholar 

  7. Shapley, L.S.: Contributions to the Theory of Games 2(28), 307 (1953)

    Google Scholar 

  8. Å trumbelj, E., Kononenko, I.: Knowl. Inf. Syst. 41(3), 647 (2014)

    Article  Google Scholar 

  9. Zeiler, M.D., Fergus, R.: European Conference on Computer Vision, pp. 818–833. Springer (2014)

    Google Scholar 

  10. Simonyan, K., Vedaldi, A., Zisserman, A.: arXiv preprint arXiv:1312.6034 (2013)

  11. Bach, S., Binder, A., Montavon, G., Klauschen, F., Müller, K.R., Samek, W.: PLoS One 10(7), e0130140 (2015)

    Article  Google Scholar 

  12. Sundararajan,, M., Taly, A., Yan, Q.: arXiv preprint arXiv:1703.01365 (2017)

  13. Merrill, J., Ward, G., Kamkar, S., Budzik, J., Merrill, D.: CoRR abs/1909.01869http://arxiv.org/abs/1909.01869 (2019)

  14. Ancona, M., Öztireli, C., Gross, M.: arXiv preprint arXiv:1903.10992 (2019)

  15. Shrikumar, A., Greenside, P., Kundaje, A.: Proceedings of the 34th International Conference on Machine Learning, vol. 70 (JMLR.org), pp. 3145–3153 (2017)

    Google Scholar 

  16. Ancona, M., Ceolini, E., Oztireli, C., Gross, M.: 6th International Conference on Learning Representations (ICLR 2018) (2018)

    Google Scholar 

  17. Erion, G., Janizek, J.D., Sturmfels, P., Lundberg, S., Lee, S.I.: arXiv preprint arXiv:1906.10670 (2019)

  18. Janzing, D., Minorics, L., Blöbaum, P.: arXiv preprint arXiv:1910.13413 (2019)

  19. Sundararajan, M., Najmi, A.: arXiv preprint arXiv:1908.08474 (2019)

  20. Krizhevsky, A., Hinton, G., et al.: Learning multiple layers of features from tiny images. Technical report, Citeseer (2009)

    Google Scholar 

  21. Cox, C.S., Feldman, J.J., Golden, C.D., Lane, M.A., Madans, J.H., Mussolino, M.E., Rothwell, S.T.: Vital and Health Statistics (1997)

    Google Scholar 

  22. Gjonça, A., Tomassini, C., Vaupel, J.W., et al.: Male-female differences in mortality in the developed world, Citeseer (1999)

    Google Scholar 

  23. Port, S., Demer, L., Jennrich, R., Walter, D., Garfinkel, A.: The Lancet 355(9199), 175 (2000)

    Article  Google Scholar 

  24. Goldwasser, P., Feldman, J.: J. Clin. Epidemiol. 50(6), 693 (1997)

    Article  Google Scholar 

  25. Paul, L., Jeemon, P., Hewitt, J., McCallum, L., Higgins, P., Walters, M., McClure, J., Dawson, J., Meredith, P., Jones, G.C., et al.: Hypertension 60(3), 631 (2012)

    Article  Google Scholar 

  26. Go, D.J., Lee, E.Y., Lee, E.B., Song, Y.W., Konig, M.F., Park, J.K.: J. Korean Med. Sci. 31(3), 389 (2016)

    Article  Google Scholar 

  27. Bao, X., Bergman, L., Thompson, R.: Proceedings of the Third ACM Conference on Recommender Systems, pp. 109–116. ACM (2009)

    Google Scholar 

  28. Güneş, F., Wolfinger, R., Tan, P.Y.: SAS Conference Proceedings (2017)

    Google Scholar 

  29. Zhai, B., Chen, J.: Sci. Total Environ. 635, 644 (2018)

    Article  Google Scholar 

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Correspondence to Hugh Chen .

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Chen, H., Lundberg, S., Lee, SI. (2021). Explaining Models by Propagating Shapley Values of Local Components. In: Shaban-Nejad, A., Michalowski, M., Buckeridge, D.L. (eds) Explainable AI in Healthcare and Medicine. Studies in Computational Intelligence, vol 914. Springer, Cham. https://doi.org/10.1007/978-3-030-53352-6_24

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