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Present Technology and Future Trends in Point-of-Care Microfluidic Diagnostics

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Microfluidic Diagnostics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 949))

Abstract

This work reviews present technologies and developing trends in Point-of-Care (POC) microfluidic diagnostics platforms. First, various fluidics technologies such as pressure-driven flows, capillary flows, electromagnetically driven flows, centrifugal fluidics, acoustically driven flows, and droplet fluidics are categorized. Then three broad categories of POC microfluidic testing devices are considered: lateral flow devices, desktop and handheld POC diagnostic platforms, and emergent molecular diagnostic POC systems. Such evolving trends as miniaturization, multiplexing, networking, new more sensitive detection schemes, and the importance of sample processing are discussed. It is concluded that POC microfluidic diagnostics has a potential to improve patient treatment outcome and bring substantial savings in overall healthcare costs.

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Notes

  1. 1.

    The term “digital microfluidics” is also used.

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Acknowledgments

This work was supported by the National Science Foundation grants ECCS-0801792 and NIRT-0709085, National Institute of Health grant 1 R01 AIO89541-01, and UC Lab Fees Award 09-LR-09-117362 and sponsored by World Class University (WCU) program (R32-2008-000-20054-0) through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology.

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Authors and Affiliations

  1. Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA, USA

    Lawrence Kulinsky, Zahra Noroozi & Marc Madou

  2. Department of Biomedical Engineering, University of California, Irvine, CA, USA

    Marc Madou

  3. Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea

    Marc Madou

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  1. Lawrence Kulinsky
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  2. Zahra Noroozi
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  3. Marc Madou
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Correspondence to Lawrence Kulinsky .

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  1. Key Laboratory for Organic Electronics &, Information Displays (KLOEID), Nanjing Univ. of Posts&Telecommunication, Jia Sheng Hua Yuan, No.2 Building Room 201, Nanjing, 210013, Jiangsu, China, People's Republic

    Gareth Jenkins

  2. Scientific & Medical Communications Cons, avenue Paul Santy 1C, Ecully, 69130, France

    Colin D. Mansfield

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Kulinsky, L., Noroozi, Z., Madou, M. (2013). Present Technology and Future Trends in Point-of-Care Microfluidic Diagnostics. In: Jenkins, G., Mansfield, C. (eds) Microfluidic Diagnostics. Methods in Molecular Biology, vol 949. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-134-9_1

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  • DOI: https://doi.org/10.1007/978-1-62703-134-9_1

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