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Design and Synthesis of Novel Functional Lipid-Based Bioconjugates for Drug Delivery and Other Applications

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Bioconjugation Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 751))

Abstract

The modification of biologicals such as proteins/peptides, small molecules, and other polymers with lipids provides an efficient method for mediating their insertion into liposomes and lipid-core micellar nanocarriers. In this chapter, we describe several representative protocols developed in our laboratory for the bioconjugation of liposomes and lipid-core micelles for drug/gene delivery and diagnostic imaging applications.

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Authors and Affiliations

  1. Department of Pharmaceutical Sciences, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA, USA

    Vladimir P. Torchilin

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  1. Rupa R. Sawant
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  2. Vladimir P. Torchilin
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Correspondence to Vladimir P. Torchilin .

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Editors and Affiliations

  1. Pacific Biosciences, Willow Road 1380, Menlo Park, 94025, California, USA

    Sonny S. Mark

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Sawant, R.R., Torchilin, V.P. (2011). Design and Synthesis of Novel Functional Lipid-Based Bioconjugates for Drug Delivery and Other Applications. In: Mark, S. (eds) Bioconjugation Protocols. Methods in Molecular Biology, vol 751. Humana Press. https://doi.org/10.1007/978-1-61779-151-2_23

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  • DOI: https://doi.org/10.1007/978-1-61779-151-2_23

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