Abstract
In this chapter, we describe the use of Illumina® Infinium® HD Assay in conjunction with Illumina’s EPIC Methylation 8-sample array platform to obtain glioblastoma molecular profiles. The procedure spans four days, and can be performed by a single laboratory technician. Starting with as little as 250 ng of DNA input, this method allows the flexibility to begin with DNA derived from either formalin-fixed, paraffin-embedded (FFPE) or fresh tissue and is compatible with an Illumina iScan or HiScan system.
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Hovestadt V, Zapatka M Enhanced copy-number variation analysis using Illumina DNA methylation arrays. conumee: R package version 1.9.0
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Serrano, J., Snuderl, M. (2018). Whole Genome DNA Methylation Analysis of Human Glioblastoma Using Illumina BeadArrays. In: Placantonakis, D. (eds) Glioblastoma. Methods in Molecular Biology, vol 1741. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7659-1_2
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DOI: https://doi.org/10.1007/978-1-4939-7659-1_2
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