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New Japanese Classification of Pancreatic Cancer

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Pancreatic Cancer

Abstract

Background: The Japanese classification of pancreatic cancer, seventh edition, has been released by Japan Pancreas Society (JPS) in July 2016.

Methods: Revision concepts and major revision points of the seventh edition of Japanese classification of the pancreatic cancers were reviewed.

Results: The principal points of revision are as follows:

  1. 1.

    Definition of the parts of the pancreas.

  2. 2.

    T category and stage grouping: consistency with those of the UICC seventh edition was obtained.

  3. 3.

    Reappraisal of anatomy of extrapancreatic nerve plexuses.

  4. 4.

    N category: classification based on numbers of lymph nodal metastasis among the regional lymph nodes; N1a, metastasis in one to three regional lymph nodes; and N1b, metastasis in four or more regional lymph nodes.

  5. 5.

    Histopathological classification which is consistent with the WHO classification.

The following new items have been added: (1) diagnostic guideline of tumor extension and lymph node metastasis based on multidetector CT (MD-CT), (2) objective criteria defining resectability status only based on the findings of MD-CT, (3) cytopathology guideline, and (4) criteria of histological response to drug therapy and/or radiotherapy.

Conclusion: The revised seventh edition of JPS pancreatic cancer classification focuses on establishing consistency to UICC seventh edition, while originality of JPS classification is maintained.

Conflicts of Interest

Shuji Isaji, Yasuhiro Murata, and Masashi Kishiwada declare that they have no competing interests.

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Author information

Authors and Affiliations

  1. Hepatobiliary Pancreatic and Transplant Surgery, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan

    Shuji Isaji, Yasuhiro Murata & Masashi Kishiwada

Authors
  1. Shuji Isaji
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  2. Yasuhiro Murata
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  3. Masashi Kishiwada
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Corresponding author

Correspondence to Shuji Isaji .

Editor information

Editors and Affiliations

  1. Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany

    John P. Neoptolemos

  2. Division of Research Department of Surgery and Genomic Sciences and Precision Medicine Center (GSPMC), Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Raul Urrutia

  3. Division of Medical Oncology, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA

    James L. Abbruzzese

  4. Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany

    Markus W. Büchler

Section Editor information

  1. Duke University Medical Center, Durham, NC, USA

    James L. Abbruzzese

  2. Mayo Clinic Cancer Center, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA

    Raul A. Urrutia

  3. Division of Surgery and Oncology, University of Liverpool, Daulby Street, Liverpool, UK

    John Neoptolemos

  4. Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany

    Markus W. Büchler

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Isaji, S., Murata, Y., Kishiwada, M. (2018). New Japanese Classification of Pancreatic Cancer. In: Neoptolemos, J., Urrutia, R., Abbruzzese, J., Büchler, M. (eds) Pancreatic Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-7193-0_84

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