Table of contents

  1. Front Matter
    Pages i-xxxiii
  2. The Nature of Pancreatic Cancer

    1. Front Matter
      Pages 1-1
    2. Patrick Maisonneuve, Albert Lowenfels
      Pages 3-18
    3. Yusuke Kojima, Reeja S. Maskey, Yuichi J. Machida
      Pages 19-49
    4. Olca Basturk, Michelle D. Reid, N. Volkan Adsay
      Pages 51-87
    5. L. Charles Murtaugh, Ondine Cleaver, Raymond J. MacDonald
      Pages 89-145
    6. Aatur D. Singhi, Anirban Maitra
      Pages 147-176
    7. Gianfranco Delle Fave, Elettra Merola, Gabriele Capurso, Stefano Festa, Matteo Piciucchi, Roberto Valente
      Pages 209-239
    8. Volker Fendrich, Detlef K. Bartsch
      Pages 241-263
    9. Lena Haeberle, Jasmin Riemer, Irene Esposito
      Pages 265-281
    10. Heather A. Lillemoe, John D. Abad, Keith D. Lillemoe
      Pages 283-312
    11. Paola Martinelli, Francisco X. Real
      Pages 313-347
    12. Mackenzie Goodwin, Ethan V. Abel, Vinee Purohit, Diane M. Simeone
      Pages 349-368
    13. David J. McConkey, Woonyoung Choi
      Pages 369-382
    14. Monique Williams, Gwen Lomberk, Raul Urrutia
      Pages 383-408
    15. Tara L. Hogenson, Rachel L. O. Olson, Martin E. Fernandez-Zapico
      Pages 409-430
    16. Kathleen A. Boyle, Michael A. James, Susan Tsai, Douglas B. Evans, Michael B. Dwinell
      Pages 481-508

About this book


In organizing the second edition of  this renowned Handbook, Dr. Neoptolemos and his co-editors have produced and updated a revised edition to the distinguished Major Reference Work devoted to pancreatic cancer. Like its preceding edition, the second edition continues to have a widespread appeal among clinicians, pathologists and basic scientists, who are now struggling to understand this complex and rapidly expanding field. Because of the recent and vast growth in both the clinical and scientific research being done in pancreatic cancer, (there is currently an unprecedented investment by academia and industry in this field), each research’s knowledge of other specialty areas outside his or her own is often quite limited. The aim of the new edition is to place the tangible advances, including new developments in surgical approaches with regards to resection techniques, the state of laparoscopic approaches, the growing impact of surgical approaches in the management of recurrent pancreatic cancer, controversies in the management of IMPN as the precursor lesion for PDAC and others – readily at hand. The second edition focuses on advances that will not become dated, and the editors have chosen authors, who are the very best in each area.


Pancreatic cancer Epidemiology of pancreatic cancer IMPN PDAC Pancreatic neuroendocrine tumors Molecular characterization of pancreatic cell lines Laparoscopy and laparoscopic ultrasound Endoscopy

Editors and affiliations

  • John P. Neoptolemos
    • 1
  • Raul Urrutia
    • 2
  • James L. Abbruzzese
    • 3
  • Markus W. Büchler
    • 4
  1. 1.Department of General, Visceral and Transplantation SurgeryUniversity of HeidelbergHeidelbergGermany
  2. 2.Division of Research Department of Surgery and Genomic Sciences and Precision Medicine Center (GSPMC)Medical College of WisconsinMilwaukeeUSA
  3. 3.Division of Medical Oncology, Duke Cancer InstituteDuke University Medical CenterDurhamUSA
  4. 4.Department of General, Visceral and Transplantation SurgeryUniversity of HeidelbergHeidelbergGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2018
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4939-7191-6
  • Online ISBN 978-1-4939-7193-0
  • About this book