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Midline Thalamus and Amygdaloid Kindling

  • Chapter
Kindling 4

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 37))

Abstract

Among the midline structures, the role of the corpus callosum (CC) in the kindling model of epilepsy has been extensively investigated. Findings suggest that the CC is not important for seizure development from the amygdala (AM), hippocampus (HIPP) and temporal cortex, but that it is the major, if not the exclusive, anatomical substratum for convulsive seizure bilateralization and the development of bisynchronous bisymmetrical generalized convulsion (27,28,32,41,52,53,55,56,57). As a first step in clarifing the possible role played by the midline structures in the elaboration of generalized seizure, we focused our attention on the nonspecific thalamus which is known to participate not only in the modulation of widespread electrocortical activity (6,16,37) but also in the propagation of cortical seizure discharges (23,24,50).

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Authors and Affiliations

  1. Divisions of Neurosciences and Neurology, University of British Columbia, Vancouver, British Columbia, V6T 2A1, Canada

    Yoshitaka Ehara & Juhn A. Wada

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  1. Yoshitaka Ehara
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  2. Juhn A. Wada
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Editors and Affiliations

  1. Neurosciences and Neurology, University of British Columbia, Vancouver, British Columbia, Canada

    Juhn A. Wada

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© 1990 Plenum Press, New York

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Ehara, Y., Wada, J.A. (1990). Midline Thalamus and Amygdaloid Kindling. In: Wada, J.A. (eds) Kindling 4. Advances in Behavioral Biology, vol 37. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5796-4_30

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  • DOI: https://doi.org/10.1007/978-1-4684-5796-4_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5798-8

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