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Free Radicals and Trials of Antioxidant Therapy in Muscle Diseases

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Antioxidants in Therapy and Preventive Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 264))

Abstract

It has been recognised for a number of years that the severest forms of the degenerative muscular dystrophies share many of the characteristics of vitamin E or selenium deficiency myopathy of animals and indeed the animal disorders have been incorrectly termed ’nutritional muscular dystrophies’ [Bradley and Fell, 1980]. The recognition that the major functions of vitamin E and selenium within the body are likely to be as antioxidants acting to inhibit the toxic effects of free radicals has prompted investigations of the possible role of free radicals in some of the human disorders, particularly myotonic and Duchenne muscular dystrophies.

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Author information

Authors and Affiliations

  1. Department of Medicine, University of Liverpool, P.O. Box 147, Liverpool, L69 3BX, UK

    M. J. Jackson & R. H. T. Edwards

Authors
  1. M. J. Jackson
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  2. R. H. T. Edwards
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Editor information

Editors and Affiliations

  1. Centre National de la Recherche Scientifique, University of Paris, Paris, France

    Ingrid Emerit

  2. Dept. of Physiology Anatomy, University of California, Berkeley, Berkeley, California, 94720, USA

    Lester Packer

  3. Institut Gustave-Roussy, 94800, Villejuif, France

    Christian Auclair

  4. Groupe de Recherche Radicaux Libres, Institut Biomédical des Cordeliers, 15, Rue de l’Ecole de Médecine, 75006, Paris, France

    Ingrid Emerit

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© 1990 Plenum Press, New York

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Jackson, M.J., Edwards, R.H.T. (1990). Free Radicals and Trials of Antioxidant Therapy in Muscle Diseases. In: Emerit, I., Packer, L., Auclair, C. (eds) Antioxidants in Therapy and Preventive Medicine. Advances in Experimental Medicine and Biology, vol 264. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5730-8_74

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  • DOI: https://doi.org/10.1007/978-1-4684-5730-8_74

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5732-2

  • Online ISBN: 978-1-4684-5730-8

  • eBook Packages: Springer Book Archive

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