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Effects of Psychological Factors on Gastrointestinal Function

  • Chapter
Pathogenesis of Functional Bowel Disease

Part of the book series: Topics in Gastroenterology ((TGEN))

Abstract

Symptoms of psychological distress are seen in the majority of patients with gastrointestinal disorders, especially patients with irritable bowel syndrom (IBS) and “functional” dyspepsia. In irritable bowel syndrome, for example, 70% or more of patients recruited through medical clinics are found to score outside the normal range on standardized psychometric tests,1–11 and 72–100% are reported to have psychiatric disorders.2,12,13 A high proportion of patients with nonulcer dyspepsia14 and nonspecific esophageal motility disorders15 also are found to have psychiatric disorders. Psychological symptoms and abnormal personality traits are found with greater than expected frequency in peptic ulcer disease,16–18 chronic vomiting,19.20 and inflammatory bowel disease,3,21 although the association of psychological distress with these disorders is less consistent22 than for IBS and nonulcer dyspepsia.

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Authors and Affiliations

  1. Division of Digestive Diseases, Francis Scott Key Medical Center, Baltimore, Maryland, 21218, USA

    William E. Whitehead

  2. Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, 21218, USA

    William E. Whitehead

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  1. William E. Whitehead
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Editors and Affiliations

  1. Inflammatory Bowel Disease Center, Harbor-UCLA Medical Center, 90502, Torrance, California, USA

    William J. Snape Jr. M.D. (Director, Professor of Medicine) (Director, Professor of Medicine)

  2. University of California-Los Angeles, 90073, Los Angeles, California, USA

    William J. Snape Jr. M.D. (Director, Professor of Medicine) (Director, Professor of Medicine)

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Whitehead, W.E. (1989). Effects of Psychological Factors on Gastrointestinal Function. In: Snape, W.J. (eds) Pathogenesis of Functional Bowel Disease. Topics in Gastroenterology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5694-3_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5694-3_3

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