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Growth Factors and Cerebral Ischemia

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Current Review of Cerebrovascular Disease

Abstract

Growth factors are endogenous signaling proteins that initiate cellular processes leading to cell survival, growth, and differentiation. They bind to high-affinity cellular receptors (receptor protein kinases), leading to phosphorylation and activation of various signal transduction pathways (eg, mitogen-activated protein kinase and phosphatidylinositol-3 kinase pathways), which in turn results in new gene expression and protein synthesis [1, 2].

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  1. Ilknur Ay
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  2. Hakan Ay
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  3. Walter J. Koroshetz
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  4. Seth P. Finklestein
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Editors and Affiliations

  1. University of Massachusetts Medical School, Worcester, Massachusetts, USA

    Marc Fisher MD (Professor of Neurology) (Professor of Neurology)

  2. Department of Neurology, University Lausanne, Lausanne, Switzerland

    Julien Bogousslavsky MD (Professor) (Professor)

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Ay, I., Ay, H., Koroshetz, W.J., Finklestein, S.P. (2001). Growth Factors and Cerebral Ischemia. In: Fisher, M., Bogousslavsky, J. (eds) Current Review of Cerebrovascular Disease. Current Medicine Group, London. https://doi.org/10.1007/978-1-4684-0001-4_3

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  • DOI: https://doi.org/10.1007/978-1-4684-0001-4_3

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