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Chromosome Jumping: A Long Range Cloning Technique

  • Chapter
Genetic Engineering

Part of the book series: Genetic Engineering ((GEPM,volume 10))

Abstract

Genetics, the correlation of changes in the phenotype with heritable changes in the DNA of cells and organisms, and the localization of these changes to genes and ultimately DNA sequences, offers a direct and unbiased way to identify and analyze the basic functions required for life at all levels of complexity. In contrast, molecular biology provides a set of powerful techniques to analyze DNA sequences, to identify gene products, and to understand molecular mechanisms. It is therefore not unexpected, that the molecular analysis of genes defined by mutations has been essential to understand many functions required for the formation and continual existence of organisms.

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Author information

Authors and Affiliations

  1. Max Planck Institut für Medizinische Forschung, Jahnstrasse 29, Heidelberg, West Germany

    Annemarie Poustka

  2. Imperial Cancer Research Fund, Lincoln’s Inn Fields, London, UK

    Hans Lehrach

Authors
  1. Annemarie Poustka
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  2. Hans Lehrach
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Editor information

Editors and Affiliations

  1. Brookhaven National Laboratory, Upton, New York, USA

    Jane K. Setlow

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© 1988 Plenum Press, New York

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Poustka, A., Lehrach, H. (1988). Chromosome Jumping: A Long Range Cloning Technique. In: Setlow, J.K. (eds) Genetic Engineering. Genetic Engineering, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7081-3_10

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  • DOI: https://doi.org/10.1007/978-1-4615-7081-3_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-7083-7

  • Online ISBN: 978-1-4615-7081-3

  • eBook Packages: Springer Book Archive

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