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Homocysteine Metabolism: From Basic Science to Clinical Medicine

  • Book
  • © 1997

Overview

Editors:
  1. Ian Graham

    1. The Adelaide Hospital, Trinity College, Dublin, Ireland

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  2. Helga Refsum

    1. Department of Clinical Biology, University of Bergen, Bergen, Norway

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  3. Irwin H. Rosenberg

    1. Jean Mayer Usda Human Nutrition Research Center on Aging, Tufts University, Boston, USA

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  4. Per Magne Ueland

    1. Department of Clinical Biology, University of Bergen, Bergen, Norway

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  5. Jill M. Shuman

    1. Tufts University School of Nutrition Science and Policy, Medford, USA

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Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 196)

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Table of contents (36 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Biochemistry and Genetic Studies

    1. Front Matter

      Pages 1-1
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    2. The Regulation of Homocysteine Metabolism

      • James D. Finkelstein
      Pages 3-9

    3. Methionine Kinetics and Balance

      • Vernon R. Young, Yong-Ming Yu, Naomi K. Fukagawa, Comasia A. Raguso
      Pages 11-22

    4. On the Formation and Fate of Total Plasma Homocysteine

      • Helga Refsum, Anne B. Guttormsen, Torunn Fiskerstrand, Per M. Ueland
      Pages 23-29

    5. Methylenetetrahydrofolate Reductase: Comparison of the Enzyme from Mammalian and Bacterial Sources

      • Christal A. Sheppard, James S. Sumner, Phillipe Goyette, Phyllis Frosst, Rima Rozen, Rowena G. Matthews
      Pages 31-35

    6. Genetics of Mammalian 5,10-Methylenetetrahydrofolate Reductase

      • Rima Rozen
      Pages 37-42

    7. Thermolabile Methylenetetrahydrofolate Reductase

      • Soo-Sang Kang, Edward L. Passen, Myunghee H. Kim, Neal Ruggie
      Pages 43-49

    8. The Long-Term Outcome in Homocystinuria

      • David E. L. Wilcken, Bridget Wilcken
      Pages 51-56

    9. Characterization of the Human and Porcine Methionine Synthases and Their Redox Partners

      • Ruma Banerjee, Zhiqiang Chen
      Pages 57-60

    10. Inherited Disorders of Folate and Cobalamin

      • David S. Rosenblatt
      Pages 61-68

    11. Molecular Genetics of Cystathionine β-Synthase in Homocystinuria and Vascular Disease

      • Jan P. Kraus
      Pages 69-76

    12. Cystathionine β-Synthase Deficiency: Metabolic Aspects

      • S. Harvey Mudd
      Pages 77-82

  3. Vitamins, Pathology, and Drug Therapy

    1. Front Matter

      Pages 83-83
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    2. Homocysteine and Other Metabolites in the Diagnosis and Follow-Up of Cobalamin and Folate Deficiencies

      • Robert H. Allen, Sally P. Stabler, David G. Savage, John Lindenbaum
      Pages 85-92

    3. Vitamin Status and Hyperhomocysteinemia in a Healthy Population

      • Johan B. Ubbink
      Pages 93-98

    4. Association Between Plasma Homocysteine, Vitamin Status, and Extracranial Carotid-Artery Stenosis in the Framingham Study Population

      • Jacob Selhub, Paul F. Jacques, Andrew G. Bostom, Ralph B. D’Agostino, Peter W. F. Wilson, Albert J. Belanger et al.
      Pages 99-109

    5. Treatment of Mild Hyperhomocysteinemia

      • Godfried H. J. Boers, Michiel van den Berg, Diana G. Franken
      Pages 111-116

    6. Folate, Vitamin B12, and Neuropsychiatry Disorders

      • Teodoro Bottiglieri
      Pages 117-126

    7. Vitamins, Homocysteine and Neural-Tube Defects

      • T. K. A. B. Eskes
      Pages 127-131
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Keywords

Reviews

`This book is a good resource for information on homocysteine. It is well organised with short and concise chapters that have lots of diagrams, figures and tables......It is well suited for professionals in the field of cardiology and for those who are basic science researchers wishing a connection with clinical applications.'
K. Cochan, M.D., Loyola University Stritch School of Medicine

Editors and Affiliations

  • The Adelaide Hospital, Trinity College, Dublin, Ireland

    Ian Graham

  • Department of Clinical Biology, University of Bergen, Bergen, Norway

    Helga Refsum, Per Magne Ueland

  • Jean Mayer Usda Human Nutrition Research Center on Aging, Tufts University, Boston, USA

    Irwin H. Rosenberg

  • Tufts University School of Nutrition Science and Policy, Medford, USA

    Jill M. Shuman

Bibliographic Information

  • Book Title: Homocysteine Metabolism: From Basic Science to Clinical Medicine

  • Editors: Ian Graham, Helga Refsum, Irwin H. Rosenberg, Per Magne Ueland, Jill M. Shuman

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4615-5771-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1997

  • Hardcover ISBN: 978-0-7923-9983-4Published: 31 December 1997

  • Softcover ISBN: 978-1-4613-7645-3Published: 05 November 2012

  • eBook ISBN: 978-1-4615-5771-5Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XIV, 279

  • Topics: Cardiology, Oncology, Internal Medicine, Nephrology

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