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Structure and Classification of Retroviruses

  • Chapter
The Retroviridae

Part of the book series: The Viruses ((VIRS))

Abstract

The retroviruses encompass a large family of infectious agents (Retroviridae) unified by a common virion structure and mode of replication. Retroviruses have been isolated from most vertebrate species in which they have been sought, and have been found to display a remarkable diversity in their association with the host. Table I gives a list of some of the more commonly encountered viruses. At the one end of the diversity, infections with some retroviruses can lead to uniformly fatal conditions, such as AIDS, a variety of malignancies, neurologic diseases, and other clinical conditions. At the other end, some retroviruses induce only a benign viremia with no outward adverse effects, and can even become established as DNA in the germ line and passed as “endogenous” viruses from generation to generation. Indeed, the line between endogenous viruses and the retrotransposable elements found in large numbers in the genome of all eukaryotes is very fine (Chapters 1 and 4). This chapter will be concerned with a discussion of general properties of the retroviruses, the structure of their virions, and their classification. Its scope will be limited to those elements which are demonstrably viruses.

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Authors and Affiliations

  1. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, 02111, USA

    John M. Coffin

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  1. University of California, San Francisco, California, USA

    Jay A. Levy

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© 1992 Springer Science+Business Media New York

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Coffin, J.M. (1992). Structure and Classification of Retroviruses. In: Levy, J.A. (eds) The Retroviridae. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3372-6_2

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  • DOI: https://doi.org/10.1007/978-1-4615-3372-6_2

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