Abstract
This paper presents an overview of the design and implementation of the prototype version of the Integrated Genomic Database (IGD) [1]. IGD should provide for a general distributed system to access information of interest for genome researchers, human geneticists, and molecular biologists. It aims to integrate the genetic data in a comprehensive database, and provide end users with a set of tools to retrieve, display, edit and analyse the data in one framework. The prototype system integrates public data of several major databases physically into a server read-only database. IGD front-end clients then allow scientists to store retrieved data in a local database, where these can be commented or edited, and, if needed, merged with local experimental data.
IGD does not attempt to replace any existing or potential future data resources. Instead, it manages communication between these resources, and provides software tools to interface them in a uniform fashion
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ritter, O., et al. “The IGD Project Documentation; InternalTechnical Report Nr.2, DKFZ Heidelberg, 1992. Available from o.ritter@dkfz-heidelberg.de.
Frenkel, K.A. “The Human Genome Project and Informatics”, Communications of the ACM, 34, 4151, 1991.
Keen, G., et al. “Access to molecular biology databases”, Mathl. Comput. Modelling, 16, 93–101, 1992.
Benson, D., Boguski, M.S., Lipman, D.J. and Ostell, J. “The National Center for Biotechnology Information.”, Genomics 6, 389–391, 1990.
Johnston, W., Lewis, S., Markowitz, V.M., McCarthy, J., Olken, F. and Zorn, M. “The Chromosome Information System”, Technical Report LBL-29675, Lawrence Berkeley Laboratory, Berkeley, CA 94720, May 1991.
Zehetner, G., and Lehrach, H. The Reference Library Database (RLDB) In “Genome News” (N. Spurr, Ed.), No. 12, pp. 49–51. Imperial Cancer Research Fund, London, 1992.
Slezak, T., Wagner, M., Yeh, M., Cantu III, R. and Branscomb, E. “Livermore’s Pragmatic Approach to Integrated Mapping for Chromosome 19”, in this book.
see the ACEDB chapter of R. Durbin in this book.
Cherry, J. M., Cartinhour, S. W. and Goodman, H. M. “AAtDB, An Arabidopsis thaliana Database”. Plant Molecular Biology Reporter volume 10, number 4, pages 308–309, 409–410, (1992).
ISO 9075: “Information Processing Systems - Database Language SQL”, 1988.
Sybase SQL Server documentation, Sybase, Inc., Emeryville, CA 94608, USA.
Szeto, E., and Markowitz, V.M. “ERDRAW 2.2 Reference Manual”, Technical Report LBL-PUB3084, Lawrence Berkeley Laboratory, May 1991.
Markowitz, V.M., and Fang W. “SDT 4.1. Reference Manual”, Technical Report LBL-27843, Lawrence Berkeley Laboratory, May 1991.
Markowitz, V.M., and Shoshani A. “QUEST Design Document”, Preliminary Draft 1.6, Lawrence Berkeley Laboratory, September 1991.
“EMBL Data Library, User Manual”, Release 28, European Molecular Biology Laboratory, Heidelberg, September 1991.
Bairoch, A. “The SWISS-PROT Protein Sequence Data Bank”, Nucleic Acids Res. 19, 2247–2249 (1991).
Pearson, P.L., Matheson, N.W., Flescher, D.C., and Robbins, R.J. “The GDB(TM) Human Genome Database Anno 1992”, Department of Medicine and Welch Medical Library, Johns Hopkins Univerisity School of Medicine, Baltimore, MD 21205–2100, USA, 1992.
McKusick, V.A., Francomano, C.A. and Antonarakis, S.E. “Mendelian inheritance in man: catalogs of autosomal dominant, autosomal recessive and X-linked phenotypes”, Johns Hopkins University Press, Baltimore, USA, 1992.
Bryant, S. “UK DNA Probe Bank”, System Specification Rev. 1.0, Imperial Cancer Research Fund, February 1991.
Lehrach, H., Drmanac, R., Hoheisel, J., Larin, Z., Lennon, G., Monaco, A.P., Nizetic, D., Zehetner, G., and Poustka, A. “Hybridization Fingerprinting in Genome Mapping and Sequencing”, Genome Analysis Volume I: Genetic and Physical Mapping, Cold Spring Habor Laboratory Press 0–87969358–4/90, 1990.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer Science+Business Media New York
About this chapter
Cite this chapter
Ritter, O. (1994). The Integrated Genomic Database (IGD). In: Suhai, S. (eds) Computational Methods in Genome Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2451-9_5
Download citation
DOI: https://doi.org/10.1007/978-1-4615-2451-9_5
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6042-1
Online ISBN: 978-1-4615-2451-9
eBook Packages: Springer Book Archive