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Table of contents (4 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Dyslipidemia, are disorders of the metabolism of soluble transporters of lipids in extracellular spaces of the human body (including blood), called lipoproteins. They are major cardiovascular risk factors, causally related with atherosclerosis and are themselves multifactorial diseases, resulting from interactions between genetic and environmental factors.
The study of genetic factors has recently taken a new path with the study of DNA as an experimental object. More than fifty genes of lipoprotein metabolism have been identified in both their physiological actions and their contribution to the pathogenesis of human dyslipidemia. The diversity of observations has refined our current knowledge of the control of lipid metabolism and energy homeostasis in living organisms beyond the limits of the cardiovascular system (e.g., brain, immune system, and development). These studies have given way to a shake-up of former phenotypic classifications, distinguishing new entities, defining targeted therapeutic strategies, providing a basis for different patterns of disease distribution in human populations.
Authors and Affiliations
Bibliographic Information
Book Title: Genetics of Dyslipidemia
Authors: Pascale Benlian
Series Title: Basic Science for the Cardiologist
DOI: https://doi.org/10.1007/978-1-4615-1517-3
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 2001
Hardcover ISBN: 978-0-7923-7362-9Published: 30 September 2001
Softcover ISBN: 978-1-4613-5593-9Published: 05 November 2012
eBook ISBN: 978-1-4615-1517-3Published: 06 December 2012
Series ISSN: 1566-0753
Edition Number: 1
Number of Pages: XI, 315
Topics: Cardiology, Human Genetics, Biochemistry, general