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In Vivo Electroporation-Mediated Gene Delivery to the Beating Heart

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Electroporation Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1121))

Abstract

Gene therapy may represent a promising alternative strategy for cardiac muscle regeneration. In vivo electroporation, a physical method of gene transfer, has recently evolved as an efficient method for gene transfer. Here, we describe two protocols involving in vivo electroporation for gene transfer to the beating heart.

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Acknowledgements

This work was supported by the Olga Mayenfisch Foundation Zürich, Switzerland, and two grants from the Swiss National Science Foundation (3200-068304 and 31000-118270/1). The authors would like to thank Mrs Laura Seidel for English and administrative assistance.

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Tevaearai, H.T., Gazdhar, A., Giraud, MN., Flück, M. (2014). In Vivo Electroporation-Mediated Gene Delivery to the Beating Heart. In: Li, S., Cutrera, J., Heller, R., Teissie, J. (eds) Electroporation Protocols. Methods in Molecular Biology, vol 1121. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4614-9632-8_19

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  • DOI: https://doi.org/10.1007/978-1-4614-9632-8_19

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4614-9631-1

  • Online ISBN: 978-1-4614-9632-8

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