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Fate and Localization of Iodine-Labelled HCG in Mice

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Pharmacology of Hormonal Polypeptides and Proteins

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 2))

Abstract

It has been shown in the past that labelling of human chorionic gonadotropin (HCG) with 1 – 2 atoms of radioactive iodine does not affect the biological, immunological and physicochemical behaviour of the hormone. (1). Furthermore, it has been established that the ovary, more than any other organ, has a capacity to concentrate HCG, and this is specific for the gonadotropic hormone. Labelled albumin or iodide were not concentrated by the ovary even when the animals were stimulated simultaneously with unlabelled HCG (1, 2).

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References

  1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165

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  2. Eshkol, A. In: Recent Research on Gonadotropinc Hormones, eds. E.T. Bell and J. A. Loraine, Edinburgh, Livingstone (1967), p. 202.

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  3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967)6:4.

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© 1968 Springer Science+Business Media New York

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Eshkol, A., Lunenfeld, B. (1968). Fate and Localization of Iodine-Labelled HCG in Mice. In: Back, N., Martini, L., Paoletti, R. (eds) Pharmacology of Hormonal Polypeptides and Proteins. Advances in Experimental Medicine and Biology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4612-5_27

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  • DOI: https://doi.org/10.1007/978-1-4614-4612-5_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-2726-2

  • Online ISBN: 978-1-4614-4612-5

  • eBook Packages: Springer Book Archive

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