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Pharmacology of Hormonal Polypeptides and Proteins

Proceedings of an International Symposium on the Pharmacology of Hormonal Polypeptides, held in Milan, Italy, September 14–16, 1967

  • Nathan Back
  • Luciano Martini
  • Rodolfo Paoletti

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 2)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Peptide and Protein Chemistry

    1. Iphigenia Photaki
      Pages 1-10
    2. A. Patchornik
      Pages 11-16
    3. Miguel A. Ondetti, John T. Sheehan, M. Bodanszky
      Pages 18-31
    4. L. Bernardi, G. Bosisio, R. de Castiglione, O. Goffredo
      Pages 32-34
    5. Garland R. Marshall
      Pages 48-52
  3. Posterior Pituitary Hormones

  4. Hypothalamic Neurohumoral Principles

  5. Anterior Pituitary Hormones

    1. G. Lugaro, M. M. Casellato, M. Motta, F. Piva, L. Martini
      Pages 167-174
    2. Q. L. Gessa, W. Ferrari
      Pages 190-195
    3. L. Szporny, Gy. T. Hajos, S. Szeberenyi, G. Fekete
      Pages 196-202
    4. Aaron B. Lerner, G. Virginia Upton, Saul Lande
      Pages 203-212
    5. Aliza Eshkol, B. Lunenfeld
      Pages 223-228
    6. P. Donini, D. Puzzuoli, I. D’Alessio, S. Donini
      Pages 229-238
    7. C. E. Grosvenor, F. Mena, D. A. Schaefgen, A. P. S. Dhariwal, J. Antunes-Rodriguez, S. M. McCann
      Pages 242-253
    8. G. Tonietti, P. Liberti, L. Grasso, A. Pinchera
      Pages 263-270
    9. G. Giordano, R. Balestreri, G. E. Jacopino, E. Foppiani
      Pages 271-274
  6. Insulin and Glucagon

    1. Panayotis G. Katsoyannis
      Pages 278-296
    2. J. Dupré, J. D. Curtis, R. Waddell, J. C. Beck
      Pages 297-303
    3. A. Benedetti, R. C. Simpson, G. M. Grodsky, P. H. Forsham
      Pages 304-312
    4. Piero P. Foà
      Pages 351-360
    5. J. G. T. Sneyd, J. D. Corbin, C. R. Park
      Pages 367-376
    6. Jean Crabbé, J. Scarlata
      Pages 377-381
    7. H. Schimassek, J. Helms, H. J. Mitzkat
      Pages 382-386
    8. P. Lefebvre, A. Cession-Fossion, A. Luyckx, J. Lecomte, H. Van Cauwenberge
      Pages 396-400
  7. Peptides Affecting Lipid Metabolism

    1. Daniel Rudman, Mario Di Girolamo, Luis A. Garcia
      Pages 401-415

About this book

Introduction

It can be concluded (under the specific experimental procedures em­ ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig­ nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport­ ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely:­ the first phase, when there is only an inflow from the circulation and stor­ age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in­ flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y. , U. S. A. andbyGrantNo.

Keywords

antibody antigen pharmacology protein research

Editors and affiliations

  • Nathan Back
    • 1
  • Luciano Martini
    • 2
  • Rodolfo Paoletti
    • 3
  1. 1.Department of Biochemical Pharmacology, School of PharmacyState University of New YorkBuffaloUSA
  2. 2.Institute of PharmacologyUniversity of MilanMilanItaly
  3. 3.Institute of PharmacologyUniversity of CagliariCagliariItaly

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4614-4612-5
  • Copyright Information Springer-Verlag US 1968
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4899-2726-2
  • Online ISBN 978-1-4614-4612-5
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site