Definition
Cobalt is relatively rare among essential trace elements but plays important roles in various living organisms. For instance, cobalamin cofactor comprising a cobalt ion coordinated in a substituted corrin macrocycle is known as vitamin B12, and its deficiency may cause severe damage to mammals. In this entry, the structure and function of vitamin B12-dependent enzymes and non-corrin cobalt enzymes are reviewed.
Introduction
Cobalt is the 27th element in the periodic table and a transition metal with seven d electrons. It can take oxidation states from –I to + IV and preferably exists as Co2+ and Co3+. Cobalt is relatively rare among essential trace elements, and its concentrations in seawater and the cytosol are 10−11 and 10−9 mol dm−3, respectively. Geochemistry of trace metals suggests that the cobalt ion existed in ancient sea in relatively high...
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Odaka, M., Kobayashi, M. (2013). Cobalt Proteins, Overview. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_69
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DOI: https://doi.org/10.1007/978-1-4614-1533-6_69
Publisher Name: Springer, New York, NY
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