Abstract
There has been a continuing interest in the role of pyridoxine (vitamin B6) in maintenance of the structure and function of the nervous system. At the International Symposium (Harris et al., 1964) on vitamin B6 in honor of Professor Paul György, Roberts et al. (1964) mentioned that “γ-amino butyric acid (GABA) plays an inhibitory or modulatory role in the central nervous sytem (CNS).” Since then, more direct evidence has accumulated to confirm both a neurotransmitter role for GABA in the vertebrate CNS and the regulation of its synthesis by pyridoxal phosphate (PALP).
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References
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Dakshinamurti, K. (1982). Neurobiology of Pyridoxine. In: Draper, H.H. (eds) Advances in Nutritional Research. Advances in Nutritional Research, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-9934-6_6
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