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Involvement of S-Adenosylmethionine in Brain Phospholipid Metabolism

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Natural Sulfur Compounds

Abstract

The synthesis of phosphatidylcholine (Ptd-choline) in animal tissues is carried out chiefly by the cytidine nucleotide pathway, although base-exchange reaction and stepwise methylation of preexisting phosphatidylethanolamine (Ptd-ethanolamine) also contribute to its formation1–7. The N-methylation pathway, first demonstrated in liver by Bremer and Greenberg3 and successively described in this tissue by several authors, has not been however unequivocally demonstrated in brain, and conflicting data have been produced in this connection8–10.

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© 1980 Plenum Press, New York

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Mozzi, R., Andreoli, V., Porcellati, G. (1980). Involvement of S-Adenosylmethionine in Brain Phospholipid Metabolism. In: Cavallini, D., Gaull, G.E., Zappia, V. (eds) Natural Sulfur Compounds. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3045-5_4

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  • DOI: https://doi.org/10.1007/978-1-4613-3045-5_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3047-9

  • Online ISBN: 978-1-4613-3045-5

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