Skip to main content
SpringerLink
Log in

Molecular Components of Hepatitis B Virus

  • Book
  • © 1985

Overview

Authors:
  1. Mark Feitelson

    1. Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, USA

    View author publications

    You can also search for this author in PubMed   Google Scholar

Part of the book series: Developments in Molecular Virology (DMVI, volume 6)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (15 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. The Molecular Components of Hepatitis B Virus

    • Mark Feitelson
    Pages 1-8

  3. Hepatitis B Surface Antigen (HBsAg)

    • Mark Feitelson
    Pages 8-63

  4. Dane Particle “Specific” Antigenic Determinants

    • Mark Feitelson
    Pages 63-64

  5. Anti-HBs Monoclonal Antibodies

    • Mark Feitelson
    Pages 64-66

  6. Dane Particles and Hepatitis B Core Antigen (HBcAg)

    • Mark Feitelson
    Pages 66-82

  7. Anti-HBc

    • Mark Feitelson
    Pages 82-87

  8. Hepatitis B e Antigen (HBeAg)

    • Mark Feitelson
    Pages 88-109

  9. The Protein Kinase Activity in HBcAg and the Proposed Nucleic Acid Binding Properties of Core Polypeptide

    • Mark Feitelson
    Pages 109-122

  10. The DNA Polymerase Activity of HBV

    • Mark Feitelson
    Pages 123-132

  11. HBV Genome Structure and Expression

    • Mark Feitelson
    Pages 132-143

  12. HBV in Hepatocellular Carcinoma and the Chronic Carrier State

    • Mark Feitelson
    Pages 143-171

  13. Nucleic Acid Sequencing of Dane Particle DNA and Expression of HBV Genes

    • Mark Feitelson
    Pages 171-219

  14. The 5′ Terminal Protein and Possible Origin of Genome Replication Associated with Hepatitis Viruses

    • Mark Feitelson
    Pages 219-224

  15. Replication Scheme for Hepatitis B and Related Viruses

    • Mark Feitelson
    Pages 224-232

  16. Conclusions

    • Mark Feitelson
    Pages 232-236

  17. Back Matter

    Pages 237-273
    Download chapter PDF
Back to top

Keywords

About this book

Since the discovery of Australia antigen and its association with type B hepatitis, molecular characterization of the components making up hepatitis B virus (RBV) have been pursued with worldwide interest. Over the past two decades, such characterization has led to the development of sensitive assays to screen and exclude contaminated units from blood banks and has recently resulted in the licensing of several RBV vaccines. That more than 200 million people worldwide are chronically infected with RBV, and that they are at a high risk for the development of chronic hepatitis and hepatocellular carcinoma, still represent formidable problems in our understanding of host-virus relationships on the molecular level. In the absence of a suitable tissue culture system, and with a very limited host range of infection, characterization of RBV on the molecular level has made remarkable progress recently with the advent of genome cloning, sequencing and expression of individual virus genes by recombinant DNA technology. The presence of hepatitis B-like viruses in an expanding number of animal hosts, and the possibility of virus replication in cells other than hepatocytes, provide great promise that future work will elucidate the molecular mechanisms operative in the various outcomes of RBV infection.

Authors and Affiliations

  • Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, USA

    Mark Feitelson

Bibliographic Information

  • Book Title: Molecular Components of Hepatitis B Virus

  • Authors: Mark Feitelson

  • Series Title: Developments in Molecular Virology

  • DOI: https://doi.org/10.1007/978-1-4613-2573-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1985

  • Hardcover ISBN: 978-0-89838-696-7Published: 31 January 1985

  • Softcover ISBN: 978-1-4612-9615-7Published: 19 November 2011

  • eBook ISBN: 978-1-4613-2573-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 274

  • Topics: Virology

Publish with us

Policies and ethics

Back to top

Search

Navigation