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Oxygen Transport in Tumors

Characteristics and Clinical Implications

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Oxygen Transport to Tissue XVII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 388))

Abstract

Experimental evidence suggests that the hypoxic fraction in solid tumors may influence its growth, may increase its malignant potential, and may reduce its sensitivity towards non-surgical treatment modalities (e.g., standard irradiation, certain anticancer drugs). The role of the tumor O2 status in radio-/chemotherapy and its impact on relevant tumor biological characteristics of tumors are summarized in Table 1.

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Author information

Authors and Affiliations

  1. Institute of Physiology and Pathophysiology, University of Mainz, D-55099, Mainz, Germany

    Peter Vaupel

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  1. Peter Vaupel
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Editors and Affiliations

  1. Academic Medical Center, Amsterdam, The Netherlands

    C. Ince  & J. Kesecioglu  & 

  2. University of Istanbul, Istanbul, Turkey

    L. Telci  & K. Akpir  & 

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© 1996 Plenum Press, New York

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Vaupel, P. (1996). Oxygen Transport in Tumors. In: Ince, C., Kesecioglu, J., Telci, L., Akpir, K. (eds) Oxygen Transport to Tissue XVII. Advances in Experimental Medicine and Biology, vol 388. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0333-6_44

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  • DOI: https://doi.org/10.1007/978-1-4613-0333-6_44

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8002-3

  • Online ISBN: 978-1-4613-0333-6

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