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Etiology and Pathogenesis of Intracranial Berry Aneurysms

  • Chapter
Intracranial Aneurysms

Abstract

Intracranial berry aneurysms have occasioned much controversy for many years, and there is still no unanimity of opinion regarding the etiology. Two basic theories are current. The first states that these aneurysms are due to mal-development or some inherent hypothetical weakness of the arterial wall—a so-called congenital theory. The second contends the aneurysms are the result of acquired degenerative changes in the vessel wall—the degeneration theory. Proponents of a third theory attribute the aneurysms to a combination of developmental and degenerative changes. Crawford (40) alleged that developmental medial defects, atherosclerosis, and hypertension play roles of varying importance according to the age at which the aneurysm develops, the only criterion for differentiating aneurysms of different etiologic types being the age of the patient.

This chapter is a continuation of Chapter 11 in which much of the groundwork is set down by same pathologist.

As in Chapter 11 the financial assistance of the Medical Research Council, the National Heart Foundation, and the Neurological Research Foundation of New Zealand is gratefully acknowledged.

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Stehbens, W.E. (1983). Etiology and Pathogenesis of Intracranial Berry Aneurysms. In: Intracranial Aneurysms. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5437-9_12

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  • DOI: https://doi.org/10.1007/978-1-4612-5437-9_12

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