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Angiogenesis-related Growth Factors in Brain Tumors

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Angiogenesis in Brain Tumors

Part of the book series: Cancer Treatment and Research ((CTAR,volume 117))

Abstract

Numerous growth factors have been implicated in glioma angiogenesis. This chapter focuses on the role of scatter factor/hepatocyte growth factor, fibroblast growth factor, platelet-derived growth factor and transforming growth factor P. We review the expression pattern of these factors in gliomas, their functional contribution to tumor angiogenesis — also in relation to vascular endothelial growth factor, and the effects resulting from their inhibition or overexpression in gliomas in vivo.

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Authors and Affiliations

  1. Department of Neurosurgery, University Hospital Hamburg-Eppendorf, Germany

    Katrin Lamszus, Oliver Heese & Manfred Westphal

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  1. Katrin Lamszus
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  2. Oliver Heese
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  3. Manfred Westphal
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Editors and Affiliations

  1. Neurosurgery Carl Gustav Carus Hospital, Technical University of Dresden, Dresden, Germany

    Matthias Kirsch

  2. Neurosurgery Children’s Hospital Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Peter McL. Black

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Lamszus, K., Heese, O., Westphal, M. (2004). Angiogenesis-related Growth Factors in Brain Tumors. In: Kirsch, M., Black, P.M. (eds) Angiogenesis in Brain Tumors. Cancer Treatment and Research, vol 117. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8871-3_12

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  • DOI: https://doi.org/10.1007/978-1-4419-8871-3_12

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