Abstract
Indocyanine green (ICG) emits near-infrared fluorescence when it is excited by near-infrared light. The near infrared fluorescence of ICG was applied to the imaging of cerebral vessels during neurosurgical operations such as clipping of aneurysms. In this study, ICG angiography was applied to extracranial-intracranial (EC-IC) bypass surgery to evaluate the hemodynamic changes induced by bypass in moyamoya disease (MD) and non-moyamoya ischemic diseases (non-MD). These patients underwent superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis. We compared the cortical areas where the bypass supplied blood flow between MD and non-MD. ICG angiography clearly demonstrated the bypass blood flow from the anastomosed STA to the cortical vessels including arteries, capillaries, and veins in both MD and non-MD. Interestingly, the anastomosed STA supplied blood flow to a larger cortical area in MD than non-MD. The bypass supplied greater extent of blood flow to the ischemic brain in MD than in non-MD. This difference might be caused by the fact that the perfusion pressure was lower in MD than in non-MD.
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References
Suzuki J (1986) Moyamoya disease. Springer Berlin Heidelberg, New York.
Khan N, Schuknecht B, Boltshauser E et al. (2003) Moyamoya disease and Moyamoya syndrome: experience in Europe; choice of revascularisation procedures. Acta Neurochir (Wien) 145:1061–1071.
Saito N, Nakagawara J, Nakamura H, et al. (2004) Assessment of cerebral hemodynamics in childhood moyamoya disease using a quantitative and a semiquantitative IMP-SPECT study. Ann Nucl Med 18:323–331.
Anderson DE, McLane MP, Reichman OH et al. (1992) Improved cerebral blood flow and CO2 reactivity after microvascular anastomosis in patients at high risk for recurrent stroke. Neurosurgery 31:26–33.
Ueno M, Nishizawa S, Toyoda H et al. (2001) Assessment of cerebral hemodynamics before and after revascularization in patients with occlusive cerebral revascularization by means of quantitative IMP-SPECT with double-injection protocol. Ann Nucl Med 15:209–215.
Benson RC, Kues HA (1978) Fluorescence properties of indocyanine green as related to angiography. Phys Med Biol 23:159–163.
Kogure K, David NJ, Yamanouchi U et al. (1970) Infrared absorption angiography of the fundus circulation. Arch Ophthalmol 83:209–214.
Bernstein M, Fleming JFR, Deck JHN (1984) Cerebral hyperperfusion after carotid endarterectomy: a cause of cerebral hemorrhage. Neurosurgery 15:50–56.
Raabe A, Beck J, Gerlach R, et al. (2003) Near-infrared indocyanine green video angiography: a new method for intraoperative assessment of vascular flow. Neurosurgery 52:132–139.
Woitzik J, Horn P, Vajkoczy P et al. (2005) Intraoperative control of extracranial-intracranial bypass patency by near-infrared indocyanine green videoangiography. J Neurosurg 102:692–698.
Hoshino T, Sakatani K, Kano T et al. (2006) Cerebral blood oxygenation changes induced by bypass blood flow in moyamoya disease and non-moyamoya cerebral ischaemic disease. Acta Neurochirurgica (Wien) 148:551–557.
Furuya K, Kawahara N, Morita A et al. (2004) Focal hyperperfusion after superficial temporal artery-middle cerebral artery anastomosis in a patient with moyamoya disease: case report. J Neurosurg 100:128–132.
Ogasawara K, Komoribayashi N, Kobayashi M et al. (2005) Neural damage caused by cerebral hyperperfusion after arterial bypass surgery in a patient with moyamoya disease: case report. Neurosurgery 56:E1380.
Piepgras DG, Morgan MK, Sundt TM et al. (1988) Intracerebral hemorrhage after carotid endarterectomy. J Neurosurg 68:532–536.
Stiver SI, Ogilvy CS (2002) Acute hyperperfusion syndrome complicating EC-IC bypass. J Neurol Neurosurg Psychiatry 73:88–89
Murata Y, Katayama Y, Sakatani K et al. (2003) Evaluation of extracranial- intracranial arterial bypass function by using near-infrared spectroscopy. J Neurosurg 99:304–310.
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Awano, T. et al. (2010). EC-IC Bypass Function in Moyamoya Disease and Non-Moyamoya Ischemic Stroke Evaluated by Intraoperative Indocyanine Green Fluorescence Angiography. In: Takahashi, E., Bruley, D. (eds) Oxygen Transport to Tissue XXXI. Advances in Experimental Medicine and Biology, vol 662. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-1241-1_75
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DOI: https://doi.org/10.1007/978-1-4419-1241-1_75
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