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Decline of Immune Responsiveness: A Pathogenetic Factor in Alzheimer’s Disease?

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Handbook on Immunosenescence

While the etiopathogenesis of Alzheimer’s disease (AD) still remains unresolved, a growing body of evidence indicates the involvement of the immune system. Yet, both character and the significance of the observed alterations are matter of dispute.

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Authors and Affiliations

  1. Department of Psychiatry and Psychotherapy, University of Tübingen, Osianderstrasse 24, Tübingen, DE-72076, Germany

    Elke Richartz-Salzburger & Niklas Koehler

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  1. Elke Richartz-Salzburger
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  2. Niklas Koehler
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Editors and Affiliations

  1. Research Center on Aging, Department of Medicine, Immunology Graduate Programme, Faculty of Medicine, University of Sherbrooke, 1036 Rue Belvedere, J1H 4C4, Sherbrooke, Quebec, Canada

    Tamas Fulop

  2. Department of Experimental Pathalogy, CIG Interdepartmental Center “L. Galvani” University of Bologna, Via San Giacomo 12, 40126, Bologna, Italy

    Claudio Franceschi

  3. Institute for Health and Life Sciences, 4-6-22 Kohinato, Bunkyo-ku, Tokyo, 112-0006, Japan

    Katsuiku Hirokawa

  4. ZMF - Zentrum Med. Forschung Abt. Transplant./ Immunologie, University of Tübingen, Waldhörnlestr. 22, 72072, Tübingen, Germany

    Graham Pawelec

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Richartz-Salzburger, E., Koehler, N. (2009). Decline of Immune Responsiveness: A Pathogenetic Factor in Alzheimer’s Disease?. In: Fulop, T., Franceschi, C., Hirokawa, K., Pawelec, G. (eds) Handbook on Immunosenescence. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-9063-9_61

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