Abstract
Although the increased incidence of common cancers with age on one hand and immunosenescence on the other are both well documented in animal models and in humans, evidence for a causal link between the two is controversial. It is, therefore, most appropriate to critically consider whether the dysfunctional immune processes occurring with aging may play a contributing role in the increased incidence of cancer with aging. Indeed whether or not immunosenescence plays a significant role could have a determinant impact on devising cancer prevention and/or immunotherapeutic strategies for the presently growing elderly population.
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Sportès, C., Hakim, F.T. (2009). Aging, Immunity and Cancer. In: Fulop, T., Franceschi, C., Hirokawa, K., Pawelec, G. (eds) Handbook on Immunosenescence. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-9063-9_55
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DOI: https://doi.org/10.1007/978-1-4020-9063-9_55
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