Overview
- Editors:
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John L. VandeBerg
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Southwest National Primate Research Center, San Antonio, USA
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Sarah Williams-Blangero
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Southwest Foundation for Biomedical Research, San Antonio, USA
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Suzette D. Tardif
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Southwest National Primate Research Center, San Antonio, USA
- First volume since 1965 to provide in depth study of Baboon in Biomedical Research
- Among all primates, baboons are the most widely used as models for the genetics of susceptibility to complex diseases and they are the first nonhuman primate for which a framework genetic linkage map was established
- In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased
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Table of contents (19 chapters)
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Front Matter
Pages i-xxiii
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- Jeffrey Rogers, Michael C. Mahaney, Laura A. Cox
Pages 1-19
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- Erika K. Honoré, Suzette D. Tardif
Pages 89-110
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- Richard Eberle, Uriel Blas-Machado, Roman F. Wolf, Gary L. White
Pages 111-138
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- Thomas M. D’Hooghe, Cleophas K. Kyama, Jason M. Mwenda
Pages 139-156
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- Andrew G. Hendrickx, Pamela E. Peterson
Pages 157-178
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- Bradley A. Yoder, Donald C. McCurnin, Jacqueline J. Coalson
Pages 179-205
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- Leslea J. Hlusko, Michael C. Mahaney
Pages 207-223
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- David L. Rainwater, John L. VandeBerg
Pages 225-236
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- Peter W. Nathanielsz, Mark J. Nijland, Christian H. Nevill, Susan L. Jenkins, Gene B. Hubbard, Thomas J. McDonald et al.
Pages 237-253
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- Glen E. Mott, Douglas S. Lewis
Pages 255-264
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- John R. Blair-West, Derek A. Denton, Robert E. Shade, Richard S. Weisinger
Pages 265-283
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- Charles S. Lieber, Maria A. Leo, Leonore M. DeCarli
Pages 285-301
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- Robert D. Hienz, Elise M. Weerts
Pages 303-325
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- Kevin J. Black, Tamara Hershey, Stephen M. Moerlein, Joel S. Perlmutter
Pages 327-350
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- C. Ákos Szabó, M. Michelle Leland, Koyle D. Knape, Jeff T. Williams
Pages 351-370
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About this book
Nonhuman primates have played critical roles in biomedical research, and they are among the few animals whose use in research continues to increase. The scienti?c value of nonhuman primates derives from their close phylogenetic proximity to man and their consequent anatomic, physiologic, and genetic similarities to man. Only nonhuman primates can provide adequate models for many complex physiological and disease processes of humans. The baboon is a relative newcomer to the repertoire of nonhuman primates used in biomedical research. However, in less than 50 years since its ?rst use in the U. S. , it has become one of the most popular laboratory primate species. It is larger than the other widely used monkey species, making it advantageous for many types of experiments and technological developments. It is extraordinarily hardy and highly fecund in captivity. It closely resembles humans in a variety of physiological and disease processes, such as cholesterol metabolism, early stages of atherosclerosis, and alcoholic liver disease. Its chromosomes closely resemble those of humans, and many genes of the two species lie in the same chromosomal order. Among all primates, baboons are the most widely used models for the genetics of susceptibility to complex diseases and they are the ?rst nonhuman primate for which a framework genetic linkage map was established. In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased.
