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The Baboon Model for Dental Development

  • Chapter
The Baboon in Biomedical Research

Part of the book series: Developments in Primatology: Progress and Prospects ((DIPR))

The dental research implications of the physiological, immunological, and morphological similarities between baboons and humans have long been recognized (Virgadamo et al., 1972; Aufdemorte et al., 1993). Applied dentistry has widely employed the baboon as a model upon which to develop procedures and techniques and to test the material biocompatibility prior to introduction into general practice on humans. For example, baboons have been used for the tests of procedures to mechanically modify jaw bone growth (Bell et al., 1999), tests of responses to allograft mixtures for bony reconstructions (Kohles et al., 2000), development for therapeutic osteogenesis and functional and morphological bone repair techniques (Ripamonti, 1992), tests of gene products (such as BMP proteins) to induce periodontal regeneration (Ripamonti et al., 2001), protocols for stabilizing jaws for treating fractures (Fisher et al., 1990), assessments of bone response to prosthetic fit (Carr et al., 1996), and tests of responses to orthodontic apparatus (Woods and Nanda, 1991).

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Authors and Affiliations

  1. Department of Integrative Biology, University of California, Berkeley, California 94720

    Leslea J. Hlusko

  2. Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245

    Michael C. Mahaney

  3. Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245

    Michael C. Mahaney

Authors
  1. Leslea J. Hlusko
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  2. Michael C. Mahaney
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Editors and Affiliations

  1. Southwest National Primate Research Center, San Antonio, TX, USA

    John L. VandeBerg  & Suzette D. Tardif  & 

  2. Southwest Foundation for Biomedical Research, San Antonio, TX, USA

    Sarah Williams-Blangero

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Hlusko, L.J., Mahaney, M.C. (2009). The Baboon Model for Dental Development. In: VandeBerg, J.L., Williams-Blangero, S., Tardif, S.D. (eds) The Baboon in Biomedical Research. Developments in Primatology: Progress and Prospects. Springer, New York, NY. https://doi.org/10.1007/978-0-387-75991-3_10

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