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Computational Methods in the Modeling of Scaffolds for Tissue Engineering

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Computational Modeling in Tissue Engineering

Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials ((SMTEB,volume 10))

Abstract

Tissue engineering uses porous biomaterial scaffolds to support the complex tissue healing process to fulfill two main functions: (1) to support mechanical loading and (2) to allow mass transport. Computational methods have been extensively applied to characterize scaffold morphology and to simulate different biological processes of tissue engineering. In addition, phenomena such a cell seeding, cell migration, cell proliferation, cell differentiation, vascularisation, oxygen consumption, mass transport or scaffold degradation can be simulated using computational methods. A review of the different methods used to model scaffolds in tissue engineering is described in this chapter.

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Author information

Authors and Affiliations

  1. Biomechanics and Mechanobiology, Institute for Bioengineering of Catalonia, Baldiri Reixac, 4, Barcelona, 08028, Spain

    Andy L. Olivares

  2. Department of Mechanical Engineering, University of Sheffield, Mappin Street, Sheffield, S1 3JD, UK

    Damien Lacroix

Authors
  1. Andy L. Olivares
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  2. Damien Lacroix
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Corresponding author

Correspondence to Damien Lacroix .

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Editors and Affiliations

  1. , Biomechanics Research Unit, University of Liège, Chemin des Chevreuils 1–BAT 52/3, Liège 1, 4000, Belgium

    Liesbet Geris

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© 2012 Springer-Verlag Berlin Heidelberg

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Olivares, A.L., Lacroix, D. (2012). Computational Methods in the Modeling of Scaffolds for Tissue Engineering. In: Geris, L. (eds) Computational Modeling in Tissue Engineering. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/8415_2012_136

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  • DOI: https://doi.org/10.1007/8415_2012_136

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-32562-5

  • Online ISBN: 978-3-642-32563-2

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